Condition

Head and Neck Cancer Squamous Cell Carcinoma clinical trials and research

• 9Clinical trials
• 4Countries

Newest Head and Neck Cancer Squamous Cell Carcinoma clinical trials

All recruiting trials (9)

• Immunotherapy with nodal-sparing radiation for head and neck cancer

  This study tests whether giving pembrolizumab before and after a focused radiation and surgery plan helps boost the immune response in patients with surgically removable head and neck squamous cell cancer.

  Recruiting Phase 2 Medical College of Wisconsin · Milwaukee, Wisconsin · NCT07773987

• Emactinib sulfate with chemotherapy and adebrelimab given before surgery for advanced head and neck cancer

  This trial tests whether giving emactinib plus adebrelimab with nab‑paclitaxel and cisplatin before surgery can shrink tumors or increase complete responses in people with locally advanced head and neck squamous cell carcinoma.

  Recruiting Phase 2 Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT07457346

• SH009 injection for advanced solid tumors

  This trial will test whether SH009 injections are safe and can shrink or slow advanced solid tumors in adults with cancers such as liver, lung, breast, head and neck, and esophageal cancer who have progressed after prior treatment.

  Recruiting Phase 1 Nanjing Sanhome Pharmaceutical, Co., Ltd. · Shanghai · NCT07390838

• Stereotactic post-operative radiation for head and neck skin squamous cell cancer involving the parotid/neck

  This trial tests whether a short, five‑session stereotactic radiation course works as well and has fewer side effects than the usual 20–30 session radiation after surgery for head and neck skin squamous cell carcinoma.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07337161

• Induction therapy with toripalimab plus cisplatin and docetaxel for head and neck squamous cell carcinoma

  This study tests whether adding toripalimab to cisplatin and docetaxel induction therapy is safe and tolerable for adults with newly diagnosed locally advanced head and neck squamous cell carcinoma.

  Recruiting at 2 sites Phase 2 Massachusetts General Hospital · Boston, Massachusetts and 1 other locations · NCT07214987

• Improved Oral Health for Head and Neck Cancer Survivors

  Aiming to see if a structured oral care program helps head and neck cancer survivors keep their mouths healthier and feel better after treatment.

  Recruiting Uppsala University · Uppsala · NCT07173270

• VS-101 combined with chemoradiotherapy for head and neck squamous cell carcinoma

  We will test whether adding the experimental drug VS-101 to standard cisplatin-based chemoradiotherapy helps adults with locally advanced head and neck squamous cell carcinoma respond better to treatment.

  Recruiting at 2 sites Phase 2 VSPharmTech Co.,Ltd. · New Haven, Connecticut and 1 other locations · NCT06959082

• Combination treatment for recurrent head and neck cancer

  This study is testing a new combination of two drugs, Surufatinib and Envolizumab, to see if they can help people with recurrent head and neck cancer feel better when other treatments haven't worked.

  Recruiting Phase 2 Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai · NCT06876844

• Using Trilaciclib to Protect Bone Marrow in Head and Neck Cancer Patients After Surgery

  This study is testing if adding a new drug called trilaciclib to standard treatment after surgery can help protect the bone marrow of patients with advanced head and neck cancer from the harmful effects of chemotherapy.

  Recruiting Phase 2 Hunan Cancer Hospital · Changsha, Hunan · NCT06752798

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Quick answers

How many Head and Neck Cancer Squamous Cell Carcinoma clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in China (4 trials), United States (3 trials), Canada (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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