Condition
Hairy Cell Leukemia clinical trials and research
As of November 12, 2026, Find a Trial lists 8 Hairy Cell Leukemia clinical trials that are recruiting, at sites in 2 countries (most in United States (7), Germany (1)). By phase: Phase 2 (3), Phase 1 (3), Phase 2/3 (1), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8Clinical trials
- 2Countries
Newest Hairy Cell Leukemia clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Tovorafenib plus rituximab for classical hairy cell leukemia | Phase 1/2 | Bethesda, Maryland and 3 other locations | Recruiting | May 11, 2025 |
| Comparing two treatment combinations for Hairy Cell Leukemia | Phase 2 | Boston, Massachusetts and 9 other locations | Recruiting | Aug 20, 2024 |
| Using CAR T cells to treat certain types of B cell lymphomas | Phase 1 | Palo Alto, California | Recruiting | Apr 1, 2024 |
| Using modified T cells to treat relapsed hairy cell leukemia | Phase 1 | Bethesda, Maryland | Recruiting | Mar 25, 2021 |
| Oral treatment with LP-168 for patients with certain blood cancers | Phase 1 | Durham, North Carolina and 3 other locations | Recruiting | Mar 1, 2021 |
| Treatment for Hairy Cell Leukemia Without BRAF Mutation | Phase 2 | Bethesda, Maryland | Recruiting | Mar 26, 2020 |
| Optimizing treatment for hairy cell leukemia with cladribine injections | Phase 2/3 | Ansbach and 75 other locations | Recruiting | May 6, 2014 |
| Combining cladribine and rituximab to treat hairy cell leukemia | Phase 2 | Houston, Texas | Recruiting | Dec 18, 2006 |
All recruiting trials (8)
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Tovorafenib plus rituximab for classical hairy cell leukemia
This trial tests whether combining tovorafenib and rituximab is safe and effective for adults with relapsed or refractory classical hairy cell leukemia and compares that combination to cladribine plus rituximab in newly diagnosed patients.
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Comparing two treatment combinations for Hairy Cell Leukemia
This study is testing whether a new combination of drugs can work better and cause fewer side effects than the standard treatment for patients with Hairy Cell Leukemia who have a specific genetic mutation.
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Using CAR T cells to treat certain types of B cell lymphomas
This study is testing a new CAR T cell therapy to see if it can help adults with certain types of B cell lymphomas that haven't improved with other treatments.
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Using modified T cells to treat relapsed hairy cell leukemia
This study is testing a new treatment using modified T cells to see if it can help adults with relapsed hairy cell leukemia who haven't responded to other therapies.
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Oral treatment with LP-168 for patients with certain blood cancers
This study is testing an oral treatment called LP-168 to see if it can help adults with certain types of blood cancers that have come back or didn't respond to other treatments.
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Treatment for Hairy Cell Leukemia Without BRAF Mutation
This study is testing if a new drug called binimetinib can help people with hairy cell leukemia who don't have a BRAF mutation and haven't responded to other treatments.
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Optimizing treatment for hairy cell leukemia with cladribine injections
This study is testing if a single round of cladribine injections can help people with untreated hairy cell leukemia go into remission.
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Combining cladribine and rituximab to treat hairy cell leukemia
This study is testing if combining two drugs, cladribine and rituximab, can effectively treat hairy cell leukemia, especially in patients whose cancer has come back.
Related topics
Quick answers
How many Hairy Cell Leukemia clinical trials are recruiting right now?
8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (7 trials), Germany (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 3, Phase 1: 3, Phase 2/3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.