Condition
H3 K27M clinical trials and research
As of November 12, 2026, Find a Trial lists 2 H3 K27M clinical trials that are recruiting, at sites in 18 countries (most in United States (2), Argentina (1), Australia (1)). By phase: Phase 1/2 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 18Countries
All recruiting trials (2)
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Treatment for young patients with relapsed or refractory brain tumors
This study is testing a new way to deliver cancer drugs directly to the brain tumors of young patients under 22 who have not responded to other treatments, to see if it helps them feel better.
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Treatment with ONC201 for patients with H3 K27M-mutant diffuse glioma after radiotherapy
This study is testing if the drug ONC201 can help people with a specific type of brain tumor live longer and stay healthier after they finish their initial radiation treatment.
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Quick answers
How many H3 K27M clinical trials are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 18 countries. The most sites are in United States (2 trials), Argentina (1 trial), Australia (1 trial), Austria (1 trial), Brazil (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.