Drug or treatment
Cetuximab clinical trials
As of November 12, 2026, Find a Trial lists 79 clinical trials of Cetuximab that are recruiting, at sites in 49 countries (most in China (41), United States (29), Spain (12)). 2 were first registered in the last 30 days. By phase: Phase 2 (46), Phase 3 (16), Phase 1/2 (10), Phase 1 (6). The most active sponsors are M.D. Anderson Cancer Center (4), Sun Yat-sen University (4), Fudan University (3). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 79Clinical trials
- 2New in 30 days
- 49Countries
Newest trials
All recruiting trials (79)
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Toripalimab Plus Cetuximab and Irinotecan for second-line right-sided colon cancer
This phase II study tests whether a combo of toripalimab, cetuximab, and irinotecan helps adults with second-line, right‑sided, RAS/BRAF wild-type advanced colon cancer.
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Iparomlimab and Tuvonralimab With Cetuximab Before Surgery in Resectable Oral Cancer
In this phase 2 study, patients with locally advanced, resectable oral squamous cell carcinoma will receive a combination of iparomlimab, tuvonralimab, and cetuximab before surgery to see if the treatment is safe and can shrink tumors.
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Cetuximab bioequivalence test in healthy men
This study tests whether a cetuximab injection is bioequivalent to Erbitux in healthy men to see if they behave the same in the body.
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HSK42360-Na tablets with cetuximab in BRAF V600-mutant metastatic colorectal cancer
This Phase 1/2 study tests whether HSK42360-Na tablets with cetuximab, with or without standard chemotherapy, are safe and may help people whose colorectal cancer has a BRAF V600 mutation that has spread.
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Neoadjuvant therapy with encorafenib plus cetuximab N01 and mFOLFOX6 in locally advanced BRAF V600E-mutant colorectal cancer
This trial tests a targeted, pre-surgery treatment to see if it improves the chance of long-term control in adults with locally advanced BRAF V600E-mutant colorectal cancer.
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Petosemtamab plus chemotherapy vs standard chemo plus cetuximab or bevacizumab in RAS/BRAF WT colorectal cancer
This phase 3 trial tests whether adding petosemtamab to standard chemotherapy works better than the usual chemo plus cetuximab or bevacizumab for people with recurrent, unresectable, or metastatic colorectal cancer that is KRAS/NRAS/BRAF wild type.
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Bevacizumab, sintilimab, cetuximab and irinotecan in refractory RAS wild-type metastatic colorectal cancer
This trial tests whether adding sintilimab to a cetuximab and irinotecan backbone, with or without bevacizumab, helps patients with heavily pretreated metastatic colorectal cancer that has RAS wild-type tumors.
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Petosemtamab plus chemotherapy vs cetuximab plus chemotherapy in left-sided unresectable or metastatic colorectal cancer
This trial tests whether adding petosemtamab to standard chemotherapy works better than cetuximab with chemotherapy for adults with left-sided, unresectable or metastatic colorectal cancer that is KRAS/NRAS wild-type.
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GFH276 with Cetuximab or chemotherapy in RAS-mutated solid tumors and PDAC
This study tests whether GFH276 combined with cetuximab or standard chemotherapy can help adults with advanced solid tumors or pancreatic cancer that carry a RAS mutation.
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KRAS G12D-mutated pancreatic cancer: VS-7375 with or without cetuximab
This study tests whether VS-7375, alone or with cetuximab, can help people with metastatic PDAC that carries the KRAS G12D mutation.
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Neoadjuvant fulzerasib plus cetuximab N01 for KRAS G12C–mutated locally advanced colorectal cancer
This trial will try a chemo-free combination of fulzerasib and cetuximab N01 before surgery in adults with KRAS G12C–mutated locally advanced colorectal cancer, including some with resectable metastases.
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Second-line combination treatment for MSS metastatic colorectal cancer
This trial will try folinic acid plus continuous 5-FU with liposomal irinotecan, sometimes combined with cetuximab or bevacizumab, as a second-line option for adults with MSS metastatic colorectal cancer who progressed on or cannot tolerate oxaliplatin-based therapy.
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Short-course radiotherapy plus intensified chemotherapy and targeted therapy with immunotherapy for high-risk rectal cancer
This trial tests whether adding targeted therapy and a PD-1 inhibitor to a short course of radiotherapy and standard chemotherapy helps high-risk pMMR/MSS rectal cancer patients, compared with the same radiotherapy and chemotherapy alone.
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BAY 3771249 for advanced colorectal cancer with KRAS G12D mutation
This trial will test whether BAY 3771249, alone or with cetuximab, helps people with advanced or metastatic colorectal cancer that has a KRAS G12D mutation.
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Cetuximab with PD-1 therapy plus chemotherapy vs PD-1 therapy with chemotherapy for recurrent/metastatic head and neck cancer
This trial tests whether adding cetuximab to a PD-1 inhibitor plus chemotherapy helps people with recurrent or metastatic head and neck squamous cell cancer who aren’t candidates for curative treatment.
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Sintilimab + ipilimumab N01 with cetuximab and dabrafenib for MSS BRAF V600E metastatic colorectal cancer
This trial will test whether combining the immunotherapies sintilimab and ipilimumab N01 with cetuximab and dabrafenib helps people with microsatellite-stable, BRAF V600E metastatic colorectal cancer live longer or have better tumor control.
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AMT-676 combinations for advanced colorectal cancer
This study tests AMT-676 together with standard chemotherapy and targeted therapies to see if it’s safe and effective for people with unresectable advanced colorectal cancer.
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Radiation plus cetuximab vs radiation plus chemotherapy for advanced head and neck cancer patients who cannot receive cisplatin
This trial tests whether adding cetuximab to radiation works as well as, or better than, radiation with carboplatin and paclitaxel for people with advanced head and neck cancers who can’t have cisplatin.
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Continuing cetuximab after first progression for metastatic colorectal cancer
This study will test whether keeping cetuximab while switching the chemotherapy backbone helps adults with RAS/BRAF wild‑type metastatic colorectal cancer whose disease progressed after first‑line anti‑EGFR therapy.
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Irinotecan plus cetuximab rechallenge versus trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer
This phase 2 trial tests whether giving irinotecan with cetuximab again helps patients with metastatic colorectal cancer whose disease progressed after standard therapies, compared with the current standard third-line treatment of trifluridine/tipiracil plus bevacizumab, using blood-based molecular profiling to select
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GFH375 combined with cetuximab or chemotherapy for KRAS G12D–mutant solid tumors
This tests whether adding GFH375 to cetuximab or to standard chemotherapy helps people with advanced solid tumors that have a KRAS G12D mutation.
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Cetuximab beta plus fruquintinib, with or without immunotherapy, for first-line treatment of RAS/BRAF wild‑type unresectable metastatic colorectal cancer
This trial tests whether combining cetuximab beta and fruquintinib, with or without immune checkpoint inhibitors, can control cancer as a chemotherapy‑free first‑line option for patients with RAS/BRAF wild‑type unresectable metastatic colorectal cancer.
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AK104 plus FOLFIRI with cetuximab or bevacizumab for second-line MSS advanced colorectal cancer
This trial tests whether adding AK104 to FOLFIRI with either cetuximab or bevacizumab helps people with MSS advanced colorectal cancer who progressed after oxaliplatin-based first-line therapy.
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Calderasib (MK-1084) with or without cetuximab for advanced KRAS G12C solid tumors
This study will test whether calderasib (MK-1084), alone or combined with cetuximab, can shrink advanced solid tumors in people whose cancers have the KRAS G12C mutation.
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HCB101 combined with cetuximab or bevacizumab plus FOLFOX/FOLFIRI for advanced metastatic colorectal cancer
This trial tries weekly HCB101 infusions together with cetuximab or bevacizumab and FOLFOX or FOLFIRI chemotherapy in adults with advanced or metastatic RAS/BRAF wild-type colorectal cancer who have progressed after prior chemotherapy.
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IBI351 with cetuximab β for previously untreated advanced KRAS G12C non-small cell lung cancer
This trial tests whether combining IBI351 with cetuximab β helps people with untreated advanced non-small cell lung cancer that has a KRAS G12C mutation.
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Sacituzumab govitecan plus cetuximab for recurrent or metastatic head and neck squamous cell cancer
This trial will test whether combining sacituzumab govitecan with cetuximab works and is safe for people whose head and neck squamous cell cancer has returned or spread after prior immunotherapy.
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Amivantamab plus hyaluronidase versus cetuximab for advanced cutaneous squamous cell carcinoma in people with weakened immune systems
This phase II trial tests whether amivantamab with hyaluronidase works better than cetuximab for people with recurrent or metastatic cutaneous squamous cell carcinoma who have a weakened immune system.
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ctDNA-guided choice of cetuximab versus bevacizumab with trifluridine/tipiracil for RAS/BRAF wild-type metastatic colorectal cancer
This trial tests whether a ctDNA blood test can help choose cetuximab plus trifluridine/tipiracil versus bevacizumab plus trifluridine/tipiracil for people with RAS/BRAF wild-type metastatic colorectal cancer who have progressed after prior treatments.
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Calderasib plus cetuximab and chemotherapy for KRAS G12C colorectal cancer
This trial will test whether adding calderasib and cetuximab to mFOLFOX6 helps people with unresectable locally advanced or metastatic colorectal cancer that has a KRAS G12C mutation live longer without their cancer growing.
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Using FOLFOX-HAIC to treat colorectal liver metastasis that can't be surgically removed
This study is testing if a new combination of chemotherapy and targeted treatments can help people with colorectal cancer that has spread to the liver and can't be surgically removed, so they can eventually have surgery and live longer.
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Combining Cetuximab, Tislelizumab, and Chemotherapy for Advanced Head and Neck Cancer
This study is testing a new combination of treatments for patients with advanced head and neck cancer to see if it helps them get better and possibly have surgery.
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Combining Dabrafenib with FOLFOX and Cetuximab/Panitumumab for Metastatic Colorectal Cancer
This study is testing if a new combination of chemotherapy and targeted treatments can help people with metastatic colorectal cancer that has a specific mutation feel better and live longer.
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Combining dalpicilib with cetuximab for treating resistant head and neck cancer
This study is testing if adding dalpicilib to cetuximab can help people with tough-to-treat head and neck cancer feel better compared to just using cetuximab alone.
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Zanzalintinib with pembrolizumab and cetuximab for recurrent or metastatic head and neck squamous cell cancer
This trial tests whether adding the oral drug zanzalintinib to pembrolizumab and cetuximab is safe and finds the best dose for adults with recurrent or metastatic head and neck squamous cell cancer.
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Combining chemotherapy with cetuximab and avelumab for advanced head and neck cancer
This study is testing a new treatment plan that combines chemotherapy with two medications, cetuximab and avelumab, to see if it helps people with advanced head and neck cancer live longer without their disease getting worse.
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Cetuximab with or without weekly paclitaxel after progression on pembrolizumab plus platinum/5‑FU for recurrent/metastatic head and neck squamous cell carcinoma
This trial tests whether adding weekly paclitaxel to cetuximab helps people with recurrent or metastatic head and neck squamous cell carcinoma whose cancer progressed after first‑line pembrolizumab plus platinum/5‑FU.
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Combination treatment for advanced colorectal cancer
This study is testing a new combination of treatments for advanced colorectal cancer to see if it can help patients live longer and feel better.
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Combining irinotecan liposomes with cetuximab and vermofenib for advanced colorectal cancer
This study is testing if a new combination of treatments can help patients with advanced colorectal cancer, who haven't responded to previous therapies, feel better and have better outcomes.
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Comparing Amivantamab with FOLFIRI to Cetuximab/Bevacizumab with FOLFIRI for Colorectal Cancer
This study is testing if a new treatment combining amivantamab with FOLFIRI can help people with certain types of colorectal cancer live longer and feel better compared to the standard treatment with cetuximab or bevacizumab plus FOLFIRI.
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Combination treatment for recurrent head and neck cancer after pembrolizumab failure
This study is testing a new combination treatment for adults with recurrent head and neck cancer who didn't respond to pembrolizumab to see if it can help them feel better and improve their health.
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Comparing two treatments for advanced left-sided colorectal cancer
This study is testing whether a new drug called amivantamab combined with standard chemotherapy works better than cetuximab with the same chemotherapy for people with advanced left-sided colorectal cancer that can't be surgically removed.
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Combining Avelumab with Standard Chemotherapy for Advanced Head and Neck Cancer
This study is testing if adding avelumab to standard chemotherapy can help people with advanced head and neck cancer live longer and feel better.
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Combination treatment for advanced colorectal cancer with BRAF V600E mutation
This study is testing a new combination treatment for advanced colorectal cancer with a specific mutation to see if it works better than the usual treatment.
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Combining cetuximab with pembrolizumab for advanced head and neck cancer
This study is testing if adding cetuximab to pembrolizumab can help people with advanced head and neck cancer live longer and feel better compared to just using pembrolizumab alone.
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Combining cetuximab, irinotecan, and a PD-1 inhibitor for treating specific colorectal cancer
This study is testing a new combination of treatments for patients with hard-to-treat right-sided colorectal cancer to see if it can help them when other options haven't worked.
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Second-line treatment for advanced colorectal cancer using new chemotherapy options
This study is testing a new combination of chemotherapy drugs to see if it can help people with advanced colorectal cancer who haven't had success with their first treatment.
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Using cemiplimab and cetuximab before surgery for recurrent oral cavity cancer
This study is testing if the drugs cemiplimab and cetuximab can help control recurrent oral cavity cancer before surgery to improve patient outcomes.
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Combination treatment for advanced colorectal cancer with specific mutations
This study is testing a combination of three drugs to see if they can help people with advanced colorectal cancer that has specific mutations after they've already tried other treatments.
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Combination therapy for metastatic colorectal cancer with BRAF-V600E mutation
This study is testing a new combination of three drugs to see if it can help people with advanced colorectal cancer that has a specific mutation feel better and live longer after their previous treatments stopped working.
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Combination treatment for advanced colorectal cancer
This study is testing a new combination of three drugs to see if it can help people with advanced colorectal cancer that hasn't responded to other treatments.
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Combination treatment for metastatic colorectal cancer
This study is testing a combination of three drugs to see if it can help patients with certain types of metastatic colorectal cancer who have previously responded well to similar treatments.
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Thalidomide improves cetuximab and chemotherapy effectiveness for left colorectal cancer
This study is testing if adding thalidomide can make cetuximab and chemotherapy work better for people with advanced left colorectal cancer that can't be surgically removed.
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Combination treatment for advanced head and neck cancer
This study is testing a new combination treatment for people with advanced head and neck cancer to see if it can boost their immune response and help fight the disease.
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Evaluating a new treatment for advanced colorectal cancer with specific genetic mutations
This study is testing a new combination treatment for people with advanced colorectal cancer that has a specific genetic mutation to see if it can help them live longer and feel better.
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Treatment of advanced head and neck cancer with SIBP-03
This study is testing a new treatment called SIBP-03 for people with advanced head and neck cancer to see if it works better than a placebo and how safe it is.
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Neoadjuvant therapy for advanced hypopharyngeal cancer
This study is testing a new combination of immunotherapy and chemotherapy to see if it can help people with advanced hypopharyngeal cancer before they have surgery.
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Combining ZEN003694 with standard chemotherapy for advanced colorectal cancer
This study is testing if a new drug called ZEN003694 can safely improve the effects of standard chemotherapy for people with advanced colorectal cancer that hasn't responded to other treatments.
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Combining ficlatuzumab with cetuximab for advanced HPV-negative head and neck cancer
This study is testing if adding a new drug called ficlatuzumab to cetuximab can help people with advanced HPV-negative head and neck cancer live longer and feel better compared to just using cetuximab with a placebo.
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Combining ulixertinib with cetuximab and encorafenib for advanced colorectal cancer
This study is testing a new combination of three drugs to see if they can safely help people with advanced colorectal cancer who haven't responded to other treatments.
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Combining cetuximab and irinotecan for treating advanced colorectal cancer
This study is testing if combining two drugs, cetuximab and irinotecan, can help patients with advanced colorectal cancer who haven't had success with other treatments.
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New treatment combination for advanced left-side colorectal cancer
This study is testing a new combination of treatments for people with advanced left-side colorectal cancer to see if it helps them live longer without the cancer getting worse compared to the standard treatment.
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Treatment for young patients with relapsed or refractory brain tumors
This study is testing a new way to deliver cancer drugs directly to the brain tumors of young patients under 22 who have not responded to other treatments, to see if it helps them feel better.
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Testing a new antibody treatment for advanced squamous cell cancers
This study is testing a new antibody treatment combined with chemotherapy for people with advanced squamous cell cancers that haven't responded to standard therapies.
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MRG003 vs cetuximab/methotrexate for RM-SCCHN after prior therapies
This trial tests whether MRG003 can help people with recurrent/metastatic squamous cell carcinoma of the head and neck who have already tried PD-1 inhibitors and platinum therapy by comparing it to cetuximab plus methotrexate as a later-line treatment.
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Oral bevacizumab-800CW and cetuximab-800CW to detect early esophageal adenocarcinoma
This trial tests whether drinking two fluorescent tracers before an endoscopy helps doctors find early esophageal adenocarcinoma in people with Barrett's esophagus or suspected dysplasia.
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Combination treatment for localized colon or upper rectum cancer with BRAF mutation
This study is testing a combination treatment of encorafenib and cetuximab for patients with localized colon or upper rectal cancer that has a specific BRAF mutation to see if it helps before surgery.
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Combination treatment of Penpulimab and Cetuximab for advanced head and neck cancer
This study is testing a new combination of two medications, Penpulimab and Cetuximab, to see if they can help people with advanced head and neck cancer who haven't had treatment before.
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Combination treatment for HER2 positive metastatic colorectal cancer
This study is testing a new combination of tucatinib, trastuzumab, and mFOLFOX6 to see if it helps people with HER2 positive metastatic colorectal cancer more than the usual treatments.
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Combining palbociclib and cetuximab for advanced head and neck cancer treatment
This study is testing if combining two drugs, palbociclib and cetuximab, can help people with advanced head and neck cancer live longer compared to using cetuximab alone.
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Treatment for elderly patients with advanced head and neck cancer using a new drug and radiation
This study is testing a new drug combined with radiation to see if it helps elderly patients with advanced head and neck cancer feel better compared to just radiation or radiation with another drug.
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Combining chemotherapy and immunotherapy for head and neck cancer treatment
This study is testing if combining chemotherapy with immunotherapy drugs can help people with head and neck cancer before surgery and possibly reduce the need for radiation therapy afterward.
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Treatment for colorectal cancer patients with liver metastases that can't be surgically removed
This study is testing two different treatment combinations to see which one helps colorectal cancer patients with liver tumors that can’t be removed by surgery live longer and possibly make their tumors operable.
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Investigation of Encorafenib and Cetuximab for BRAF-mutated Metastatic Colorectal Cancer
This study is testing if the combination of encorafenib and cetuximab can help people with advanced colorectal cancer that has a specific genetic mutation feel better and live longer after other treatments.
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Cetuximab treatment for advanced head and neck cancer after immunotherapy
This study is testing if the drug Cetuximab can help people with advanced head and neck cancer who didn’t respond to or couldn’t tolerate previous immunotherapy treatments.
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Treatment for Stage IV Colorectal Cancer with Folfiri and Cetuximab
This study is testing if a combination of Folfiri and Cetuximab can help people with stage IV colorectal cancer who have a specific gene type feel better and improve their treatment results.
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Treatment of newly diagnosed glioblastoma using targeted drug infusion
This study is testing a new way to deliver a targeted drug directly to the brain tumor in people with newly diagnosed glioblastoma to see if it can improve their treatment outcomes.
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Targeting brain tumors with a specific drug infusion and re-irradiation
This study is testing a new way to deliver a drug directly to brain tumors in patients with certain aggressive types of glioblastoma to see if it can improve treatment results.
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Comparing chemotherapy combinations for advanced head and neck cancer
This study is testing two different chemotherapy combinations to see which one works better for people with advanced head and neck cancer while they also receive radiation therapy.
Quick answers
How many clinical trials of Cetuximab are recruiting right now?
79, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 49 countries. The most sites are in China (41 trials), United States (29 trials), Spain (12 trials), Italy (11 trials), France (10 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 46, Phase 3: 16, Phase 1/2: 10, Phase 1: 6. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.