Condition

GIST clinical trials and research

• 9Clinical trials
• 9Countries

Newest GIST clinical trials

All recruiting trials (9)

• GIST Patient Registry for real-world insights

  This registry collects medical information from people with GIST to see how the disease behaves in real life and to help improve care.

  Recruiting The Life Raft Group · Wayne, New Jersey · NCT07697248

• Comparing EFTR versus STER for removing small gastric GISTs

  This trial will test whether endoscopic full-thickness resection (EFTR) or submucosal tunneling endoscopic resection (STER) is better at completely removing small (1.0–3.5 cm) gastric GISTs in adults.

  Recruiting Chinese University of Hong Kong · Shanghai and 3 other locations · NCT07411118

• KQB198 plus imatinib for first-line advanced or metastatic GIST

  This Phase 2 test will see if adding the experimental drug KQB198 to imatinib helps people with advanced or metastatic GIST who are starting first-line treatment.

  Recruiting at 17 sites Phase 2 Kumquat Biosciences Inc. · Los Angeles, California and 16 other locations · NCT07406633

• Lenvatinib for advanced GIST after imatinib, sunitinib, and regorafenib

  This trial tests whether the oral drug lenvatinib can help people with metastatic or advanced GIST whose disease has progressed on imatinib, sunitinib, and regorafenib.

  Recruiting Phase 1/2 Asan Medical Center · Seoul · NCT07096609

• Olverembatinib for treating SDH-deficient GIST

  This study is testing if a new medication called olverembatinib can help people with a specific type of gastrointestinal tumor feel better after they’ve already tried one other treatment.

  Recruiting Phase 3 Ascentage Pharma Group Inc. · Guangzhou, Guangdong · NCT06640361

• Lutetium Lu 177 Edotreotide dose-finding for children with SSTR-positive tumors

  This test gives Lutetium Lu 177 Edotreotide to children ages 2 to under 18 with somatostatin receptor–positive tumors to find a safe pediatric dose and see how the drug behaves in the body.

  Recruiting at 9 sites Phase 1 ITM Solucin GmbH · Palo Alto, California and 8 other locations · NCT06441331

• Long-term outcomes of endoscopic procedures for upper gastrointestinal cancers

  This study looks at how well certain endoscopic procedures work for treating larger upper gastrointestinal cancers and what the long-term results are for patients.

  Recruiting Western Sydney Local Health District · Sydney, New South Wales · NCT05804331

• Monitoring targeted therapy drugs in patients with advanced digestive cancers

  This study is testing how to best monitor and adjust the doses of targeted therapy drugs for people with advanced digestive cancers to make sure they are safe and effective.

  Recruiting at 19 sites Unicancer · Amiens and 28 other locations · NCT05443087

• Investigating genetic factors in childhood cancer

  This study is trying to find out if certain genes passed down in families can increase the risk of childhood cancer by looking at samples from kids who have had cancer and their relatives.

  Recruiting St. Jude Children's Research Hospital · Memphis, Tennessee · NCT03050268

Related topics

Quick answers

How many GIST clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (4 trials), France (2 trials), China (2 trials), Spain (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 1/2: 1, Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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