Condition

Erdheim-Chester Disease clinical trials and research

• 6Clinical trials
• 2Countries

Newest Erdheim-Chester Disease clinical trials

All recruiting trials (6)

• Dabrafenib and trametinib for rare cancers with BRAF V600 mutations

  This arm tests whether dabrafenib and trametinib can help adults, children, and teens with cancers that have a BRAF V600 mutation.

  Recruiting at 15 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT07440290

• Follow-up on health outcomes in patients with histiocytic disorders

  This study looks at the long-term health effects of histiocytic disorders on around 6000 patients to see how these conditions impact their overall well-being and quality of life.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05915208

• Combination of vemurafenib and cobimetinib for treating BRAF positive cancers

  This study is testing if the combination of vemurafenib and cobimetinib can help adults with different types of cancers that have a specific BRAF mutation.

  Recruiting at 16 sites Phase 2/3 Cancer Research UK · Belfast and 15 other locations · NCT05768178

• Imaging of tumors using a specific PET scan agent

  This study is testing a new PET scan agent to see if it can help find and understand tumors in patients with different blood cancers and solid tumors.

  Recruiting Early Phase 1 Memorial Sloan Kettering Cancer Center · New York, New York · NCT05093335

• Using cobimetinib to treat refractory Langerhans cell histiocytosis and other histiocytic disorders

  This study is testing if a drug called cobimetinib can help people with hard-to-treat Langerhans cell histiocytosis and other similar disorders feel better.

  Recruiting at 10 sites Phase 2 Baylor College of Medicine · Phoenix, Arizona and 11 other locations · NCT04079179

• Registry for patients with Erdheim-Chester Disease and other histiocytoses

  This study is collecting information from people with Erdheim-Chester Disease and other histiocytoses to better understand their experiences and improve care for these conditions.

  Recruiting Memorial Sloan Kettering Cancer Center · New York, New York · NCT03329274

Related topics

Quick answers

How many Erdheim-Chester Disease clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), United Kingdom (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2/3: 2, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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