Drug or treatment

Cobimetinib clinical trials

• 4Clinical trials
• 3Countries

Newest trials

All recruiting trials (4)

• Belvarafenib plus cobimetinib for NRAS-mutant advanced or metastatic melanoma

  This trial will test whether taking belvarafenib with cobimetinib can shrink tumors or control disease in adults with NRAS‑mutant advanced or metastatic melanoma.

  Recruiting at 4 sites Phase 2 Hanmi Pharmaceutical Company Limited · Seongnam-si, Gyeonggi-do and 9 other locations · NCT07449754

• Treatment for high-risk thyroid cancer with BRAF mutation

  This study is testing if a combination of two medications can help people with high-risk thyroid cancer that has a specific mutation feel better before they receive radioactive iodine treatment.

  Recruiting Phase 2 City of Hope Medical Center · Duarte, California · NCT06440850

• Combination of vemurafenib and cobimetinib for treating BRAF positive cancers

  This study is testing if the combination of vemurafenib and cobimetinib can help adults with different types of cancers that have a specific BRAF mutation.

  Recruiting at 16 sites Phase 2/3 Cancer Research UK · Belfast and 15 other locations · NCT05768178

• Using cobimetinib to treat refractory Langerhans cell histiocytosis and other histiocytic disorders

  This study is testing if a drug called cobimetinib can help people with hard-to-treat Langerhans cell histiocytosis and other similar disorders feel better.

  Recruiting at 10 sites Phase 2 Baylor College of Medicine · Phoenix, Arizona and 11 other locations · NCT04079179

Quick answers

How many clinical trials of Cobimetinib are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (2 trials), United Kingdom (1 trial), South Korea (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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