Condition

Langerhans Cell Histiocytosis clinical trials and research

• 6Clinical trials
• 2Countries

Newest Langerhans Cell Histiocytosis clinical trials

All recruiting trials (6)

• Low-dose cytarabine combined with thalidomide for adults with newly diagnosed LCH

  This trial tests whether combining low-dose cytarabine with thalidomide is safe and effective for adults newly diagnosed with multisystem or multifocal Langerhans cell histiocytosis.

  Recruiting Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing · NCT07187193

• Targeted treatment for Langerhans Cell Histiocytosis using trametinib

  This study is testing if trametinib, a new targeted therapy, can help children with Langerhans Cell Histiocytosis feel better and avoid the harsh side effects of traditional chemotherapy.

  Recruiting Phase 2 Cook Children's Health Care System · Fort Worth, Texas · NCT06582745

• Evaluating FCN-159 for treating pediatric patients with recurrent LCH

  This study is testing a new medication called FCN-159 to see if it can help children aged 2 to 16 with recurring Langerhans cell histiocytosis feel better.

  Recruiting at 2 sites Phase 2 Fosunpharma · Beijing, Beijing Municipality and 10 other locations · NCT05997602

• Follow-up on health outcomes in patients with histiocytic disorders

  This study looks at the long-term health effects of histiocytic disorders on around 6000 patients to see how these conditions impact their overall well-being and quality of life.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05915208

• Using cobimetinib to treat refractory Langerhans cell histiocytosis and other histiocytic disorders

  This study is testing if a drug called cobimetinib can help people with hard-to-treat Langerhans cell histiocytosis and other similar disorders feel better.

  Recruiting at 10 sites Phase 2 Baylor College of Medicine · Phoenix, Arizona and 11 other locations · NCT04079179

• Comparing vinblastine/prednisone and cytarabine for treating Langerhans Cell Histiocytosis

  This study is testing whether a combination of vinblastine and prednisone works better than cytarabine alone for treating Langerhans Cell Histiocytosis in kids and young adults.

  Recruiting at 10 sites Phase 3 Baylor College of Medicine · Palo Alto, California and 10 other locations · NCT02670707

Related topics

Quick answers

How many Langerhans Cell Histiocytosis clinical trials are recruiting right now?

6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (4 trials), China (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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