POLE gene changes in high-risk endometrial cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational, single-center analysis will review high-risk and recurrent endometrial cancer cases treated at a tertiary referral hospital and perform POLE mutation testing on available tumor samples. The prevalence of POLE mutations in this real-world high-risk population will be reported. Clinical outcomes including recurrence and overall survival will be compared between POLE-mutant and non-mutant cases using survival analysis and appropriate statistical methods. The dataset is retrospective and limited to patients treated at Far Eastern Memorial Hospital.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* women with high-risk for recurrent endometrial cancer

Exclusion Criteria:

* Nil

Where it's running

• Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital
  Banqiao District, New Taipei, Taiwan Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.