Condition

Duchenne Muscular Dystrophy (DMD) clinical trials and research

• 25Clinical trials
• 2NIH research projects
• 3New in 30 days
• 13Countries

Newest Duchenne Muscular Dystrophy (DMD) clinical trials

All recruiting trials (25)

• How chronic pain changes over time in kids with Duchenne Muscular Dystrophy

  This study is following children and teens with Duchenne Muscular Dystrophy for 6 months to see how their chronic pain changes and how it affects daily life.

  Recruiting Antalya Training and Research Hospital · Antalya, Antalya · NCT07892196

• Bone health in adults with Duchenne muscular dystrophy: osteoporosis, fractures, and treatment

  This study looks at how common bone problems and fractures are in adults with Duchenne muscular dystrophy and what factors from childhood might affect bone health later on.

  Recruiting at 15 sites Istituto Giannina Gaslini · Bologna and 14 other locations · NCT07890883

• Respiratory progression in adults with Duchenne muscular dystrophy: a long-term observational study

  This study tests how respiratory function changes over three years in adults with genetically confirmed Duchenne muscular dystrophy.

  Recruiting at 13 sites Istituto Giannina Gaslini · Bologna and 12 other locations · NCT07879989

• Modeling heart failure in Duchenne and Becker muscular dystrophy to find surrogate heart measures

  This study will look at heart disease in people with Duchenne/Becker muscular dystrophy and carriers to see if MRI-based heart measures can predict death or major heart problems.

  Recruiting at 9 sites Vanderbilt University Medical Center · Sacramento, California and 8 other locations · NCT07674758

• Duchenne/Becker Muscular Dystrophy EHR Data Linkage

  This study tests whether consented patients’ electronic health records can be linked with the Duchenne Registry data to create a richer view of Duchenne and Becker muscular dystrophy care.

  Recruiting at 11 sites The Duchenne Registry · Little Rock, Arkansas and 10 other locations · NCT07609394

• Zeleciment Rostudirsen (DYNE-251) for Duchenne Muscular Dystrophy in Ambulatory Boys

  This trial tests whether intravenous Zeleciment Rostudirsen (DYNE-251) given every 4 weeks is safe and helps improve function in ambulatory boys with Duchenne muscular dystrophy who have a specific dystrophin gene mutation.

  Recruiting Phase 3 Dyne Therapeutics · Hillsborough, North Carolina · NCT07608432

• DMD gene changes and heart function in boys and young men with dystrophinopathies

  This study will test whether specific DMD gene changes and routine heart tests (blood biomarkers, ECG, and echocardiography) can help identify early heart problems in boys and young men aged 2–24 with genetically confirmed dystrophinopathies.

  Recruiting Aristotle University Of Thessaloniki · Thessaloniki · NCT07515235

• Use of invasive home ventilation in Denmark

  This project will see how often people with neuromuscular diseases or spinal cord injuries in Denmark used invasive home mechanical ventilation between 2016 and 2025 and what their one-year outcomes were.

  Recruiting Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT07467187

• Remote monitoring approach to track movement in young boys with Duchenne muscular dystrophy

  A remote, watch-based method is being tested to see if it can accurately track how boys with Duchenne muscular dystrophy move, especially for ages 1-3.

  Recruiting University of Oxford · Oxford · NCT07423026

• Duchenne/Becker Muscular Dystrophy Registry for patients and carriers

  This registry tests whether patients with Duchenne or Becker muscular dystrophy, or symptomatic female carriers, can be enrolled and followed across specialist centers to improve data sharing and care.

  Recruiting at 19 sites University Hospital Heidelberg · Graz and 29 other locations · NCT07402122

• Urine titin test for Duchenne and Becker muscular dystrophy

  We will test whether a urine test that measures a titin fragment can track muscle injury in people with Duchenne or Becker muscular dystrophy and in healthy volunteers.

  Recruiting Children's Hospital of Philadelphia · Philadelphia, Pennsylvania · NCT07332013

• Remote monitoring of motor development in newborn-identified children with SMA or DMD

  This project will try wearable sensors at home to see if they can track motor development in infants and toddlers diagnosed with spinal muscular atrophy or Duchenne muscular dystrophy through newborn or family screening.

  Recruiting Centre Hospitalier Universitaire de Liege · Liège · NCT07286565

• SPOT-03 IV gene therapy to deliver dystrophin in boys with Duchenne muscular dystrophy

  This trial will test whether intravenous SPOT-03 is safe and increases dystrophin in ambulatory boys aged 2 to under 8 with Duchenne muscular dystrophy.

  Recruiting Early Phase 1 Shanghai Siponuoyin Biotechnology Co Ltd · Shanghai, Shanghai Municipality · NCT07188012

• SGLT2 inhibitor therapy for Duchenne cardiomyopathy in kids

  This study tests whether empagliflozin can be safely given to children with Duchenne muscular dystrophy to help their heart condition and understand how the drug behaves in their bodies.

  Recruiting Phase 1 Vanderbilt University Medical Center · Nashville, Tennessee · NCT07172971

• Reducing fear of falling in people with muscular dystrophy

  This study tests whether adding cognitive-behavioral therapy to motor rehabilitation helps people aged 16–65 with muscular dystrophy who have a persistent fear of falling.

  Recruiting Universita di Verona · Verona, verona · NCT07129954

• Baby Duchenne: Tracking development in boys with Duchenne muscular dystrophy during their first three years

  This project will follow boys with Duchenne muscular dystrophy found by newborn screening to see how they grow and develop from birth through age three.

  Recruiting at 2 sites University of Rochester · Rochester, New York and 3 other locations · NCT07092540

• VR-based upper limb training for kids and teens with Duchenne muscular dystrophy

  This study tests whether immersive virtual reality plus standard physical therapy improves arm and hand function in young people with Duchenne muscular dystrophy compared with standard therapy alone.

  Recruiting Istanbul University · Istanbul, Fatih · NCT07039799

• ENTR-601-45 for Duchenne muscular dystrophy patients amenable to exon 45 skipping

  This trial will test whether ENTR-601-45 given by intravenous infusions is safe and helps boys and young men with Duchenne muscular dystrophy who are amenable to exon 45 skipping.

  Recruiting at 14 sites Phase 1/2 Entrada Therapeutics, Inc. · Ghent and 14 other locations · NCT07038824

• ENTR-601-44 treatment for Duchenne muscular dystrophy eligible for exon 44 skipping

  This trial will test whether intravenous ENTR-601-44 is safe and helps boys and young men with Duchenne muscular dystrophy whose genetics make them eligible for exon 44 skipping, compared with a placebo.

  Recruiting at 13 sites Phase 1/2 Entrada Therapeutics, Inc. · Ghent and 13 other locations · NCT07037862

• Interviews with patients and caregivers about Duchenne Muscular Dystrophy

  This study is talking to people with Duchenne Muscular Dystrophy and their caregivers to hear about their daily lives and how they feel about their independence and quality of life.

  Recruiting Red Nucleus Enterprise Solutions, LLC · Yardley, Pennsylvania · NCT06925269

• Evaluating LE051 for treating Duchenne Muscular Dystrophy

  This study is testing a new intravenous treatment called LE051 to see if it is safe and effective for people with Duchenne Muscular Dystrophy who can benefit from a specific type of therapy.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06900049

• Identifying walking-related digital biomarkers in rare childhood neuromuscular disorders

  This study is testing if special insoles with sensors can help track walking patterns in kids with spinal muscular atrophy or Duchenne muscular dystrophy to better understand their mobility.

  Recruiting at 3 sites Columbia University · Palo Alto, California and 2 other locations · NCT06839469

• Monitoring non-invasive ventilation at home for patients with Duchenne muscular dystrophy

  This study is testing whether using video and CO2 monitoring at home can help track how well non-invasive ventilation works for people with Duchenne muscular dystrophy.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT06773988

• Evaluating muscle movement patterns and quality of life in patients with Duchenne Muscular Dystrophy.

  This study is testing how trunk muscle movements in people with Duchenne Muscular Dystrophy relate to their quality of life and other factors like pain and upper limb function.

  Recruiting Seoul National University Hospital · Seoul · NCT06755138

• Evaluating BBM-D101 for treating Duchenne Muscular Dystrophy

  This study is testing a new gene therapy called BBM-D101 to see if it can help boys aged 4 to 8 with Duchenne Muscular Dystrophy improve their muscle function and slow down the disease.

  Recruiting Early Phase 1 Shanghai Jiao Tong University School of Medicine · Shanghai, Shanghai Municipality · NCT06641895

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• 3D printed human heart model for Duchenne muscular dystrophy (DMD) cardiomyopathy progression

  A patient-friendly 3D-printed heart model using stem cells and gene editing helps study how DMD affects the heart over time and tests potential therapies.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11369821

• Developing new treatments for Duchenne Muscular Dystrophy using oligonucleotides

  This study is looking for a new way to help boys with Duchenne Muscular Dystrophy by using special treatments that could boost a protein called utrophin to improve their muscle strength and health.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10678195

Related topics

Quick answers

How many Duchenne Muscular Dystrophy (DMD) clinical trials are recruiting right now?

25, as of November 12, 2026. 3 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (8 trials), Italy (5 trials), Belgium (4 trials), United Kingdom (3 trials), China (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 3, Phase 1/2: 2, Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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