How chronic pain changes over time in kids with Duchenne Muscular Dystrophy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, prospective observational study of pediatric DMD patients aged 7-18. Participants will be assessed at baseline and after 6 months for chronic pain, pain characteristics, coping strategies, and functional performance. Pain will be measured with the Adolescent Pediatric Pain Tool and the Brief Pain Inventory, while coping will be evaluated using the Pediatric Pain Coping Inventory; comparisons will be made between ambulatory and non-ambulatory patients. The study aims to describe how pain prevalence, distribution, duration, and impact differ by disease stage and to explore associated coping mechanisms. The setting is the Neuromuscular Diseases Center at Antalya Training and Research Hospital, with geographic limits to Antalya residents to minimize follow-up loss.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Genetically confirmed diagnosis of Duchenne Muscular Dystrophy (DMD)
* Aged 7 to 18 years
* Residing in Antalya, Turkey (geographical restriction applied to minimize patient travel burden and prevent loss to follow-up over the 6-month observation period)
* Intact hearing and vision capability sufficient to complete test instructions and self-report forms
* Voluntary willingness to participate, with signed informed consent from parents/legal guardians and informed assent from the child

Exclusion Criteria:

* Bedridden status (inability to sit or maintain basic seated posture)
* History of tracheostomy
* Severe intellectual disability that precludes understanding instructions
* Severe speech or communication impairment preventing self-report assessments
* Presence of co-existing psychiatric or neurodevelopmental conditions (e.g., autism spectrum disorder, attention deficit hyperactivity disorder \[ADHD\])

Where it's running

• University of Health Sciences Antalya Training and Research Hospital, Neuromuscular Diseases Center
  Antalya, Antalya, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: beyza deveci, MD — +90 242 249 44 00

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.