Evaluating muscle movement patterns and quality of life in patients with Duchenne Muscular Dystrophy.
Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns During Functional Upper Extremity Movements Among Patients with Duchenne Muscular Dystrophy Using Surface Electromyography and Computer Vision Analysis.
This study is testing how trunk muscle movements in people with Duchenne Muscular Dystrophy relate to their quality of life and other factors like pain and upper limb function.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 11 Years to 30 Years |
| Sex | All |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06755138 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD) using advanced computer vision technology. It will investigate the correlation between these movement patterns and factors such as scoliosis, upper limb function, pain levels, and overall quality of life during functional movements. Participants will include individuals diagnosed with DMD and a healthy control group, with assessments including Cobb angle measurements and upper limb function evaluations. The study seeks to understand how these patterns and their relationships evolve over time.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 10 to 30 with a confirmed diagnosis of Duchenne Muscular Dystrophy and specific muscle strength criteria.
Not a fit: Patients with severe cognitive impairment or those unable to provide informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of muscle compensation in DMD, potentially leading to improved management strategies for patients.
How similar studies have performed: While the use of computer vision in assessing muscle patterns is innovative, similar studies have shown promise in understanding movement disorders, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
1. Inclusion Criteria (1) Duchenne Muscular Dystrophy (DMD) Group
* Individuals with a confirmed genetic diagnosis of Duchenne Muscular Dystrophy.
* Aged over 10 years but under 30 years.
* Brooke Scale score between 2 and 5.
* Shoulder abductor muscle strength below grade 3 on the Manual Muscle Test (MMT).
(2) Healthy Control Group
* Individuals with no history or current diagnosis of musculoskeletal or neuromuscular disorders.
* Aged over 10 years but under 30 years.
* Shoulder muscle strength of grade 4+ or higher on the Manual Muscle Test (MMT).
* Individuals capable of understanding a detailed explanation of the study procedures and voluntarily providing written informed consent.
2. Exclusion Criteria (1) Duchenne Muscular Dystrophy (DMD) Group
* Individuals unable or unwilling to provide informed consent.
* Brooke Scale score of 1 or 6.
* Severe cognitive impairment preventing the performance of simple tasks. (2) Healthy Control Group
* Individuals unable or unwilling to provide informed consent.
* Shoulder muscle strength of grade 4 or lower on the Manual Muscle Test (MMT).
Where this trial is running
Seoul
- Seoul National University Hospital — Seoul, South Korea (Recruiting)
Study contacts
- Study coordinator: Sungbae Jo Research professor, Ph. D
- Email: rew277@gmail.com
- Phone: 82-10-9381-2299
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.