Evaluating muscle movement patterns and quality of life in patients with Duchenne Muscular Dystrophy.
Official title: Research on the Relationship Between Scoliosis, Pain, Quality of Life, and Trunk Muscle Compensation Patterns During Functional Upper Extremity Movements Among Patients with Duchenne Muscular Dystrophy Using Surface Electromyography and Computer Vision Analysis.
Run by Seoul National University Hospital · NCT06755138 · Data updated 2026-11-12
This study is testing how trunk muscle movements in people with Duchenne Muscular Dystrophy relate to their quality of life and other factors like pain and upper limb function.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 11 Years to 30 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Seoul National University Hospital Academic / other |
| Locations | 1 site (Seoul) |
| Status | Recruiting |
| Started | December 24, 2024 |
| Main results expected | July 31, 2026 |
| Study ends | August 31, 2026 |
| Registry record updated | January 1, 2025 |
| Trial ID | NCT06755138 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 10 to 30 with a confirmed diagnosis of Duchenne Muscular Dystrophy and specific muscle strength criteria.
✕Probably not a fit
Patients with severe cognitive impairment or those unable to provide informed consent may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess trunk muscle compensatory movement patterns in patients with Duchenne Muscular Dystrophy (DMD) using advanced computer vision technology. It will investigate the correlation between these movement patterns and factors such as scoliosis, upper limb function, pain levels, and overall quality of life during functional movements. Participants will include individuals diagnosed with DMD and a healthy control group, with assessments including Cobb angle measurements and upper limb function evaluations. The study seeks to understand how these patterns and their relationships evolve over time.
Why it matters
Potential benefit: If successful, this study could enhance understanding of muscle compensation in DMD, potentially leading to improved management strategies for patients.
How similar studies have gone: While the use of computer vision in assessing muscle patterns is innovative, similar studies have shown promise in understanding movement disorders, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
1. Inclusion Criteria (1) Duchenne Muscular Dystrophy (DMD) Group
* Individuals with a confirmed genetic diagnosis of Duchenne Muscular Dystrophy.
* Aged over 10 years but under 30 years.
* Brooke Scale score between 2 and 5.
* Shoulder abductor muscle strength below grade 3 on the Manual Muscle Test (MMT).
(2) Healthy Control Group
* Individuals with no history or current diagnosis of musculoskeletal or neuromuscular disorders.
* Aged over 10 years but under 30 years.
* Shoulder muscle strength of grade 4+ or higher on the Manual Muscle Test (MMT).
* Individuals capable of understanding a detailed explanation of the study procedures and voluntarily providing written informed consent.
2. Exclusion Criteria (1) Duchenne Muscular Dystrophy (DMD) Group
* Individuals unable or unwilling to provide informed consent.
* Brooke Scale score of 1 or 6.
* Severe cognitive impairment preventing the performance of simple tasks. (2) Healthy Control Group
* Individuals unable or unwilling to provide informed consent.
* Shoulder muscle strength of grade 4 or lower on the Manual Muscle Test (MMT).
Where it's running
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Seoul National University Hospital
Seoul, South Korea Recruiting
Study contacts
- Study coordinator: Sungbae Jo Research professor, Ph. D
- Email: rew277@gmail.com
- Phone: 82-10-9381-2299
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How chronic pain changes over time in kids with Duchenne Muscular Dystrophy
This study is following children and teens with Duchenne Muscular Dystrophy for 6 months to see how their chronic pain changes and how it affects daily life.
-
Bone health in adults with Duchenne muscular dystrophy: osteoporosis, fractures, and treatment
This study looks at how common bone problems and fractures are in adults with Duchenne muscular dystrophy and what factors from childhood might affect bone health later on.
-
Respiratory progression in adults with Duchenne muscular dystrophy: a long-term observational study
This study tests how respiratory function changes over three years in adults with genetically confirmed Duchenne muscular dystrophy.
-
Modeling heart failure in Duchenne and Becker muscular dystrophy to find surrogate heart measures
This study will look at heart disease in people with Duchenne/Becker muscular dystrophy and carriers to see if MRI-based heart measures can predict death or major heart problems.
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Duchenne/Becker Muscular Dystrophy EHR Data Linkage
This study tests whether consented patients’ electronic health records can be linked with the Duchenne Registry data to create a richer view of Duchenne and Becker muscular dystrophy care.
-
Zeleciment Rostudirsen (DYNE-251) for Duchenne Muscular Dystrophy in Ambulatory Boys
This trial tests whether intravenous Zeleciment Rostudirsen (DYNE-251) given every 4 weeks is safe and helps improve function in ambulatory boys with Duchenne muscular dystrophy who have a specific dystrophin gene mutation.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.