Condition

Diabetic Macular Edema clinical trials and research

• 19Clinical trials
• 12Countries

Newest Diabetic Macular Edema clinical trials

All recruiting trials (19)

• Blepharoptosis After Repeated Anti-VEGF Injections in One Eye

  This study tests whether repeated intravitreal anti-VEGF injections in one eye affect eyelid position compared with the untreated fellow eye.

  Recruiting Fatih Sultan Mehmet Training and Research Hospital · Istanbul · NCT07821450

• Testing Different Doses of BI 3812465 in Diabetic Macular Edema

  Researchers are testing whether varying doses of BI 3812465 can be tolerated in adults with center-involved diabetic macular edema.

  Recruiting at 26 sites Phase 1/2 Boehringer Ingelheim · Phoenix, Arizona and 28 other locations · NCT07553429

• Comparing AVT29 and Eylea HD for diabetic macular edema

  This study will test whether AVT29 works as well and is as safe as Eylea HD in adults with center-involving diabetic macular edema who have reduced vision.

  Recruiting Phase 3 Alvotech Swiss AG · Budapest · NCT07489131

• Daily oral Kamuvudine-9 (K9) for diabetic macular edema

  This trial will test whether taking oral K9 twice daily is safe and improves vision in adults with diabetic macular edema.

  Recruiting Phase 1/2 Vistar Eye Center · Roanoke, Virginia · NCT07458061

• RO7823653 injections, alone or with faricimab, for diabetic macular edema

  This research tests injections of RO7823653, given alone or with faricimab, in people with diabetic macular edema to see if the medication is safe and how the eye handles it.

  Recruiting at 12 sites Phase 1 Genentech, Inc. · Peoria, Arizona and 11 other locations · NCT07425522

• Lactobacillus plantarum 299v Probiotic for Diabetic Macular Edema

  A probiotic pill taken twice daily for four months is tested to see if it can help people with diabetic macular edema see better or need fewer eye injections.

  Recruiting Phase 2 Massachusetts Eye and Ear Infirmary · Boston, Massachusetts · NCT07383701

• Early progression of non-center diabetic macular edema after phacoemulsification

  This will see if non-center-involving diabetic macular edema worsens in the early weeks after cataract surgery in adults with diabetes.

  Recruiting Ain Shams University · Cairo · NCT07038967

• Blood and OCT biomarkers in people with diabetic macular edema receiving anti-VEGF or dexamethasone implant

  This project will test whether blood markers and OCT imaging signs can predict how people with diabetic macular edema respond to anti-VEGF injections or a dexamethasone eye implant.

  Recruiting Vastra Gotaland Region · Mölndal and 1 other locations · NCT06984822

• Gene therapy for diabetic macular edema in adults

  This study is testing a new gene therapy called RGX-314 to see if it can improve vision in adults with diabetic macular edema compared to the standard treatment.

  Recruiting Phase 2 Sierra Eye Associates · Reno, Nevada · NCT06942520

• Testing THN391 for Diabetic Macular Edema

  This study is testing a new drug called THN391 to see if it can safely help people with diabetic macular edema caused by diabetes.

  Recruiting at 8 sites Phase 1 Therini Bio, Inc. · Parramatta, New South Wales and 9 other locations · NCT06701721

• Home-based monitoring for diabetic macular edema treatment

  This study is testing if using home-based monitoring tools can help people with diabetic macular edema keep their vision stable while reducing the need for frequent trips to the clinic.

  Recruiting at 4 sites Zhongshan Ophthalmic Center, Sun Yat-sen University · Dongguan, Guangdong and 3 other locations · NCT06610747

• Comparing single-session and multiple-session laser treatment for diabetic eye disease

  This study is testing whether one session or multiple sessions of laser treatment works better for people with newly diagnosed diabetic eye disease to help them keep their vision and avoid complications.

  Recruiting Vastra Gotaland Region · Mölndal · NCT06549023

• Gene therapy for diabetic macular edema

  This study is testing a new gene therapy injection to see if it can improve vision and eye health in people with diabetic macular edema.

  Recruiting Phase 1/2 Frontera Therapeutics · Tianjin, Tianjin,China · NCT06492876

• Gene therapy for diabetic macular edema

  This study is testing a new gene therapy to see if it can help people with diabetic macular edema improve their vision and reduce the number of treatments they need.

  Recruiting Phase 1 Frontera Therapeutics · Tianjin, Tianjin,China · NCT05916391

• Assessing OCU200 for Diabetic Macular Edema

  This study is testing a new treatment called OCU200 to see if it can help people with diabetic macular edema while keeping them safe.

  Recruiting at 5 sites Phase 1 Ocugen · Deerfield Beach, Florida and 4 other locations · NCT05802329

• Comparing two eye implants for treating resistant diabetic macular edema

  This study tests which of two eye implants can help people with stubborn diabetic macular edema see better and improve their eye health.

  Recruiting Phase 4 Centre Hospitalier Universitaire Dijon · Dijon · NCT04910503

• Treatment for diabetic retinopathy with MS-553

  This study is testing a new oral medication called MS-553 to see if it can improve vision and reduce swelling in the eyes of people with diabetic retinopathy.

  Recruiting at 3 sites Phase 1 MingSight Pharmaceuticals, Inc · Changsha, Hunan and 2 other locations · NCT04187443

• Levosulpiride treatment for diabetic eye conditions

  This study is testing if a medication called levosulpiride can help improve eye problems caused by diabetes in people aged 40 to 69.

  Recruiting at 2 sites Phase 2 Universidad Nacional Autonoma de Mexico · Querétaro City, Querétaro and 1 other locations · NCT03161652

• Switching from ranibizumab to aflibercept for eye conditions

  This study is testing if switching patients with certain eye conditions from one medication to another can help improve their vision.

  Recruiting Medical University of Vienna · Vienna · NCT02669953

Related topics

Quick answers

How many Diabetic Macular Edema clinical trials are recruiting right now?

19, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in United States (6 trials), China (4 trials), Sweden (2 trials), Mexico (1 trial), Turkey (Türkiye) (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 5, Phase 2: 3, Phase 1/2: 3, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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