Comparing single-session and multiple-session laser treatment for diabetic eye disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to compare the safety and effectiveness of single-session versus multiple-session panretinal photocoagulation (PRP) in treating proliferative diabetic retinopathy (PDR), a leading cause of blindness in working-age adults. Both treatment approaches are commonly used, but their comparative outcomes remain debated. The study will include patients with newly diagnosed PDR and will assess visual acuity and retinal health following treatment. The goal is to determine which method is more beneficial for preserving vision and reducing complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years.
* Patients with type 1 or type 2 Diabetes Mellitus with newly diagnosed Proliferative Diabetic Retinopathy, PDR.
* Visual acuity ≥ 0.1 Snellen.
* CRT of less than 300 micrometer measured by OCT without cysts in the neuroretina.
* Clear media and adequately dilated pupil for PRP.

Exclusion Criteria:

* Intraocular surgery within the last 4 months or planned within the next 3 months.
* Previous or current center-involved diabetic macular edema (Ci-DME).
* Previous PRP, intravitreal treatment (IVT), or macular laser treatment in study eye.
* Treatment with medications known to risk macular edema.
* Media opacity preventing adequate PRP.
* General medical condition making office laser treatment very difficult or impossible.

Where it's running

• Ögonmottagning Mölndal/SU
  Mölndal, Sweden Recruiting

Study contacts

• Principal investigator: Marita Andersson Grönlund, M.D. Prof — Göteborg University
• Study coordinator: Imadeddin Abu Ishkheidem, M.D.
• Email: imadeddin.abu.ishkheidem@vgregion.se
• Phone: +46738744867

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.