Condition
Diabetes Type 2 clinical trials and research
As of November 12, 2026, Find a Trial lists 25 Diabetes Type 2 clinical trials that are recruiting, at sites in 13 countries (most in United States (11), Denmark (4), India (1)). 1 was first registered in the last 30 days. By phase: Phase 2/3 (1), Phase 1 (1), Phase 4 (1). The most active sponsors are Scripps Whittier Diabetes Institute (2), Tulane University (2), Steno Diabetes Center Copenhagen (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 25Clinical trials
- 1New in 30 days
- 13Countries
Newest Diabetes Type 2 clinical trials
All recruiting trials (25)
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Cardio-Metabolic Clinic care for adults with type 2 diabetes and cardiovascular disease
This trial tests whether a specialized Cardio-Metabolic Clinic can improve heart function and overall health for adults with type 2 diabetes and cardiovascular disease compared with usual care.
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See if short-term supervised resistance training improves muscle health and function in frail older adults with type 2 diabetes
This study tests whether a brief, supervised resistance training program can improve skeletal muscle health and physical function in frail adults over 65 who have type 2 diabetes.
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Empagliflozin, Metformin, or both for muscle energy in adults with type 2 diabetes
This study tests whether empagliflozin, metformin, or their combination can improve skeletal muscle oxidative capacity and microvascular reactivity in adults recently diagnosed with type 2 diabetes.
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Perioperative Meditation Music for Type 2 Diabetes Patients Undergoing Elective Surgery
We’re testing whether playing self-selected meditation music around surgery helps adults with type 2 diabetes stay calm, sleep better, and keep blood sugar steadier.
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How metformin works in people with or without the SLC16A11 risk variant
This study tests whether the SLC16A11 genetic variant changes how adults with type 2 diabetes respond to metformin over 6 months.
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Remote-patient monitoring in diabetes care shows real-world outcomes
A real-world, pre-post observational study at Steno Diabetes Center Copenhagen tests whether adding remote-patient-monitoring within the EHR can maintain glycemic outcomes over two years for about 12,000 people with diabetes compared with prior ambulatory care.
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GLP-1 receptor agonists and dry eye in adults with type 2 diabetes and obesity
This study tests whether GLP-1 receptor agonists affect dry eye disease in adults with type 2 diabetes and obesity.
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Digital support to reduce salt intake for people with type 2 diabetes and kidney disease
This project will test whether a smartphone app can help people with type 2 diabetes and moderately reduced kidney function eat less salt and follow kidney-friendly protein guidance over six months.
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Brain insulin resistance and brain health in people with diabetes
This project will test whether brains that don't respond well to insulin in people aged 50–80 with type 1 or type 2 diabetes are linked to worse thinking and structural brain changes compared with people without diabetes.
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Magnetic anastomosis to create a partial jejuno-ileal diversion
This will try a new endoscopic magnetic device to create a partial jejuno‑ileal diversion in adults with obesity and type 2 diabetes to help improve blood sugar and weight control.
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Community participatory learning to prevent and control type 2 diabetes in rural Kabul
This project will try a community-led participatory learning and action program to prevent and control type 2 diabetes among adults living in rural Kabul.
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FELLAship program to improve heart and metabolic health in Black men
This program will try a 24-week, church-based combination of exercise and health education to see if it improves blood pressure, cholesterol, blood sugar, and weight for Black men age 18 and older in the Birmingham area.
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Pregnancy and postpartum breastfeeding support for people with gestational diabetes
This project will try a co-designed breastfeeding support program for pregnant and postpartum people with gestational diabetes to help lower their future risk of type 2 diabetes.
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Connected care to manage type 2 diabetes with a personalized mobile app
This project will see if a personalized mobile app linked to your clinic's electronic record helps adults with type 2 diabetes in the Marche region lower their HbA1c compared with usual care.
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Continuous glucose monitoring for adults with type 2 diabetes in underserved communities
This project will test whether giving continuous glucose monitors to uninsured or Medicaid-insured adults with type 2 diabetes who take daily insulin helps them manage their blood sugar better than standard fingerstick monitoring.
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Improving diabetes care by treating insomnia with CBT-I
A pilot test to see if a 6-week CBT-I program added to usual diabetes care helps sleep and diabetes control for adults with type 2 diabetes and insomnia in an FQHC setting.
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How people with diabetes find and use health information in Reunion and mainland France
This project will see how well people with type 1, type 2, or gestational diabetes in Reunion and France understand and use health information by having them complete a single health literacy questionnaire.
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Survey to determine eligibility for cardiovascular and obesity clinical trials
This study is trying to see if people with heart issues or obesity can join new clinical trials by having them fill out a survey and undergo some health checks.
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Exploring how macrophages affect fat metabolism in obesity
This study tests how a specific protein in immune cells affects fat processing in people with obesity compared to those who are lean.
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Improving diabetes education with real-time glucose monitoring
This study is testing whether using a Continuous Glucose Monitoring device along with a text messaging program can help people with Type 2 Diabetes who don’t use insulin manage their condition better.
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Improving diabetes management for Black and Hispanic patients
This study is testing different types of support for Black and Hispanic adults with uncontrolled type 2 diabetes to see which helps them manage their condition better.
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Nutrition therapy program for obesity and diabetes in low-income individuals
This study tests a special meal replacement program to see if it helps low-income people with obesity and diabetes lose weight and manage their blood sugar better.
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Using canagliflozin to reduce vascular inflammation in patients with diabetes and coronary artery disease
This study is testing if the medication canagliflozin can help reduce inflammation in the blood vessels of people with diabetes and coronary artery disease.
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Innovative digital self-management for Type 2 diabetes
This study is testing a new digital program to help underserved Hispanic and Latino adults with Type 2 diabetes manage their health better using mobile technology and group support.
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Understanding how genetics affect response to GLP1R agonists in obesity and diabetes
This study is testing how genetics affect the way overweight or obese people from the Old Order Amish community respond to the diabetes medication semaglutide.
Related topics
Quick answers
How many Diabetes Type 2 clinical trials are recruiting right now?
25, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 13 countries. The most sites are in United States (11 trials), Denmark (4 trials), India (1 trial), Canada (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1, Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.