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Colon Cancer Stage III clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Colon Cancer Stage III clinical trials that are recruiting, at sites in 7 countries (most in Belgium (1), Germany (1), Italy (1)). By phase: Phase 3 (2), Phase 2 (1), Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 7Countries
Newest Colon Cancer Stage III clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Neoadjuvant dostarlimab before surgery for resectable stage III pMMR/MSS colon cancer | Phase 2 | Leuven | Recruiting | Feb 17, 2025 |
| Personalized treatment for high-risk colon cancer using liquid biopsy | Phase 3 | Berlin and 25 other locations | Recruiting | Jul 8, 2024 |
| Neoadjuvant chemotherapy versus immediate surgery for high-risk colon cancer | Phase 3 | Guangzhou, Guangdong | Recruiting | Jan 18, 2022 |
| mFOLFIRINOX versus mFOLFOX as additional treatment for high-risk stage III colon cancer | Phase 2/3 | Daejeon | Recruiting | Jan 6, 2022 |
| Using virtual reality to help manage pain in GI cancer patients | — | Los Angeles, California | Recruiting | Jun 1, 2021 |
All recruiting trials (5)
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Neoadjuvant dostarlimab before surgery for resectable stage III pMMR/MSS colon cancer
This will test whether two pre-surgery infusions of the PD-1 drug dostarlimab help people with resectable stage III pMMR/MSS colon cancer.
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Personalized treatment for high-risk colon cancer using liquid biopsy
This study is testing whether personalized treatment based on blood tests can help high-risk colon cancer patients do better after surgery compared to standard chemotherapy.
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Neoadjuvant chemotherapy versus immediate surgery for high-risk colon cancer
This study is testing whether giving chemotherapy before surgery can help people with high-risk colon cancer live longer and healthier compared to having surgery right away.
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mFOLFIRINOX versus mFOLFOX as additional treatment for high-risk stage III colon cancer
This trial will test whether giving mFOLFIRINOX instead of mFOLFOX after surgery helps people with high-risk stage III colon cancer (pT4N1/2 or any pT with N2) stay cancer-free longer.
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Using virtual reality to help manage pain in GI cancer patients
This study is testing if virtual reality can help people with GI cancer manage their severe abdominal pain better than standard treatments.
Related topics
Quick answers
How many Colon Cancer Stage III clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 7 countries. The most sites are in Belgium (1 trial), Germany (1 trial), Italy (1 trial), Spain (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.