Condition

Gastrointestinal Neoplasms clinical trials and research

• 16Clinical trials
• 29Countries

Newest Gastrointestinal Neoplasms clinical trials

All recruiting trials (16)

• Preoperative Muscle Health and Postoperative Outcomes in Older Adults with GI Cancer

  This study looks at whether having sarcopenia before surgery affects recovery and complications after GI cancer surgery in people 60 and older.

  Recruiting Van Training and Research Hospital · Van, Van · NCT07817758

• Velzatinib for advanced GIST after multiple prior TKIs

  This study tests velzatinib to see if it can shrink or slow tumors in people with metastatic or unresectable GIST who have progressed on or could not tolerate standard therapies.

  Recruiting at 3 sites Phase 2 GlaxoSmithKline · Fukuoka and 2 other locations · NCT07689201

• Romiplostim N01 plus ATRA for persistent low platelets after cancer remission

  This study tests whether adding all-trans retinoic acid to Romiplostim N01 helps people who still have low platelets after GI/digestive system cancer remission reach safer platelet levels.

  Recruiting Phase 2 Peking University People's Hospital · Beijing · NCT07586813

• Fecal transplant for chemotherapy and targeted-therapy gut side effects in advanced gastrointestinal cancer

  This trial will try oral fecal microbiota transplants (FMT) to see if they reduce chemotherapy or targeted-therapy–related gut symptoms in adults with advanced gastrointestinal cancers.

  Recruiting Phase 1 Second Affiliated Hospital, Zhejiang University, School of Medicine · Zhejiang, Hangzhou · NCT07319364

• PF-08634404 plus chemotherapy for adults with metastatic colorectal cancer

  This trial will test whether adding a new drug called PF-08634404 to standard chemotherapy helps adults whose colorectal cancer has spread.

  Recruiting at 343 sites Phase 3 Pfizer · Chandler, Arizona and 371 other locations · NCT07222800

• IDRX-42 versus sunitinib for adults with advanced gastrointestinal stromal tumors after imatinib

  This test compares IDRX-42 (GSK6042981) with sunitinib in adults with advanced or unresectable GIST who have already been treated with imatinib to see which controls the cancer better and is safer.

  Recruiting at 156 sites Phase 3 GlaxoSmithKline · Phoenix, Arizona and 155 other locations · NCT07218926

• GSK5764227 for adults with advanced unresectable gastrointestinal cancers

  This test tries the drug GSK5764227, alone or with other treatments, in adults with advanced gastrointestinal cancers that cannot be removed by surgery and who have had prior therapy.

  Recruiting at 85 sites Phase 1/2 GlaxoSmithKline · Los Alamitos, California and 84 other locations · NCT06885034

• Testing JNJ-89402638 for advanced colorectal cancer

  This study is testing a new drug called JNJ-89402638 to see if it is safe and what the right dose is for people with advanced colorectal cancer that hasn't responded to other treatments.

  Recruiting at 12 sites Phase 1 Janssen Research & Development, LLC · Tucson, Arizona and 11 other locations · NCT06663319

• Comparing two imaging techniques for gastrointestinal surgeries

  This study is testing two different imaging methods to see which one better helps doctors check blood flow in patients who have had gastrointestinal surgeries.

  Recruiting at 2 sites Saint Petersburg State University, Russia · Yantai, Shandong and 2 other locations · NCT06222645

• Combination treatment for ctDNA positive gastric cancer

  This study is testing a new combination treatment for patients with a specific type of stomach cancer to see if it works better than the usual treatment.

  Recruiting Phase 2 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT05494060

• Combination of Anlotinib and TQB2450 for Esophageal Cancer Treatment

  This study is testing if combining two medications, Anlotinib and TQB2450, can help people with esophageal cancer stay cancer-free after surgery.

  Recruiting Phase 2 Jiangxi Provincial Cancer Hospital · Nanchang, Jiangxi · NCT05252078

• Pooling clinical experiences of patients treated with Lutetium-177 in Spain

  This study looks at how well Lutetium-177 works and how safe it is for patients with certain types of tumors in Spain by collecting information from their medical records.

  Recruiting at 11 sites Sociedad Española de Medicina Nuclear e Imagen Molecular · Santiago de Compostela, A Coruña and 19 other locations · NCT04949282

• Using virtual reality to help manage pain in GI cancer patients

  This study is testing if virtual reality can help people with GI cancer manage their severe abdominal pain better than standard treatments.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT04907643

• Exploring the relationship between the immune system and gastrointestinal cancers

  This study is trying to see how the immune system and the environment around tumors affect how long people with gastrointestinal cancers, like colorectal and pancreaticobiliary cancers, can survive.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt · NCT04363983

• Second-line FOLFIRI +/- Bevacizumab vs Irinotecan +/- Bevacizumab in Metastatic Colorectal Cancer

  This trial tests whether a second-line FOLFIRI-based regimen with or without Bevacizumab is as good as Irinotecan-based therapy with or without Bevacizumab for patients with metastatic colorectal cancer.

  Recruiting Phase 3 Sun Yat-sen University · Guangzhou, Guangdong · NCT03303495

• Evaluating outcomes of endoscopic treatment for gastrointestinal lesions

  This study tests how well endoscopic treatment works for patients with potentially harmful gastrointestinal growths and looks at safety and survival rates after the procedure.

  Recruiting California Pacific Medical Center Research Institute · San Francisco, California · NCT01750619

Related topics

Quick answers

How many Gastrointestinal Neoplasms clinical trials are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 29 countries. The most sites are in China (8 trials), United States (6 trials), Spain (5 trials), France (4 trials), Japan (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 3, Phase 1: 2, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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