Condition

Chronic Rhinosinusitis With Nasal Polyps clinical trials and research

• 12Clinical trials
• 9Countries

Newest Chronic Rhinosinusitis With Nasal Polyps clinical trials

All recruiting trials (12)

• Mepolizumab with or without in-office nasal polypectomy for chronic rhinosinusitis with nasal polyps

  This study tests whether adding mepolizumab, alone or with in-office nasal polypectomy, helps adults with chronic rhinosinusitis with nasal polyps who need biologic treatment.

  Recruiting at 7 sites Phase 4 Instituto de Investigación Marqués de Valdecilla · Barakaldo and 6 other locations · NCT07814924

• Tezepelumab for Chinese adults with nasal polyps: a 24-week treatment study

  This trial tests whether tezepelumab can improve nasal polyps and symptoms in Chinese adults with chronic rhinosinusitis with nasal polyps who are starting therapy.

  Recruiting at 34 sites Phase 3 AstraZeneca · Beijing and 33 other locations · NCT07520162

• Reducing how often biologic injections are given for chronic nasal polyps

  This study will test whether spacing out mepolizumab or dupilumab injections to every 6–8 weeks keeps symptoms controlled in adults with partly controlled chronic rhinosinusitis with nasal polyps.

  Recruiting at 3 sites Phase 4 Copenhagen University Hospital, Rigshospitalet · Aalborg and 8 other locations · NCT07187583

• Sinonasal microbiome transplant for chronic rhinosinusitis

  This will try a sinonasal microbiome transplant to see if it reduces symptoms in people with chronic rhinosinusitis with or without nasal polyps.

  Recruiting Phase 2/3 Region Skane · Helsingborg · NCT07184684

• SHR-1905 injection for chronic rhinosinusitis with nasal polyps

  This trial will test whether SHR-1905 injections help adults with chronic rhinosinusitis with nasal polyps reduce polyp size and symptoms compared with placebo.

  Recruiting Phase 3 Guangdong Hengrui Pharmaceutical Co., Ltd · Shanghai, Shanghai Municipality · NCT07132827

• Investigating the effects of Dupilumab on nasal barrier function in chronic rhinosinusitis patients

  This study is testing if the medication Dupilumab can improve the nasal barrier function in people with chronic rhinosinusitis, especially those with nasal polyps.

  Recruiting Medical University of Vienna · Vienna, Austria · NCT06398873

• Understanding Basal Cell Function in Chronic Rhinosinusitis with Nasal Polyps

  This study is trying to understand how certain cells in the nose work differently in people with chronic sinus issues and nasal polyps compared to healthy individuals.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT06129552

• Using 3D printing to enhance nasal irrigation for chronic rhinosinusitis

  This study is testing if 3D printed models of patients' noses can help people with chronic rhinosinusitis use nasal irrigation more effectively and feel better without surgery.

  Recruiting Ohio State University · Columbus, Ohio · NCT06118554

• Observational study on biological treatments for severe chronic rhinosinusitis with nasal polyps

  This study is looking at how well new biological treatments work for adults with severe chronic sinus issues and nasal polyps, while also checking how these treatments affect symptoms over time.

  Recruiting University Hospital, Ghent · Ghent · NCT05938972

• Identifying biomarkers for response to mepolizumab in patients with nasal polyps and asthma

  This study is testing if mepolizumab can help people with nasal polyps and asthma feel better, while also looking for signs that show who will benefit from the treatment.

  Recruiting at 2 sites Aristotle University Of Thessaloniki · Thessaloniki, Exochi and 1 other locations · NCT05708300

• Investigating Inflammatory Patterns in Asthma and Nasal Polyps

  This study is trying to see how asthma and nasal polyps are connected by looking at patients with both conditions to better understand their inflammation patterns.

  Recruiting Medical University of Vienna · Vienna · NCT05009758

• Examining sleep issues in patients with nasal polyps

  This study looks at how nasal polyps affect sleep quality and whether surgery can help improve sleep for people who haven't found relief with other treatments.

  Recruiting University Hospital, Lille · Lille · NCT03725956

Related topics

Quick answers

How many Chronic Rhinosinusitis With Nasal Polyps clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in China (2 trials), Austria (2 trials), Belgium (2 trials), Spain (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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