Condition

Nasal Polyps clinical trials and research

• 12Clinical trials
• 1NIH research projects
• 11Countries

Newest Nasal Polyps clinical trials

All recruiting trials (12)

• Metabolic and Immunologic Biomarkers in Chronic Rhinosinusitis with Nasal Polyps

  This study tests whether metabolic and immune markers in nasal tissue and blood differ between people with nasal polyps and those without, to help understand CRSwNP and find potential diagnostic clues.

  Recruiting Harran University · Sanliurfa, Şanlıurfa · NCT07860411

• GSK5784283 as add-on therapy for chronic rhinosinusitis with nasal polyps

  This study tests whether GSK5784283 added to standard care can help adults with chronic rhinosinusitis with nasal polyps feel better and have fewer symptoms.

  Recruiting at 8 sites Phase 3 GlaxoSmithKline · Los Angeles, California and 7 other locations · NCT07782970

• GSK5784283 as add-on maintenance therapy for nasal polyps in chronic rhinosinusitis

  This study tests whether adding GSK5784283 (Felcorekibart) to standard care helps people with chronic rhinosinusitis with nasal polyps.

  Recruiting at 4 sites Phase 3 GlaxoSmithKline · Sherman Oaks, California and 3 other locations · NCT07782957

• Triamcinolone-loaded nanocapsules after endoscopic nasal surgery

  This trial tests whether a triamcinolone acetonide–loaded nanocapsule spray is better than saline irrigation for healing after endoscopic nasal surgery in adults with chronic rhinosinusitis and nasal polyps.

  Recruiting Phase 2 Deraya University · Minya, Menia Governorate · NCT07714525

• Depemokimab monotherapy for chronic rhinosinusitis with nasal polyps in Japanese adults

  This study tests depemokimab alone (without intranasal corticosteroids) in adults with chronic rhinosinusitis with nasal polyps in Japan.

  Recruiting at 10 sites Phase 4 GlaxoSmithKline · Ehime and 9 other locations · NCT07701967

• Stopping mepolizumab or dupilumab to see if nasal polyps stay in complete remission.

  This trial will test whether adults with well-controlled nasal polyps who have been on mepolizumab or dupilumab can safely stop the biologic and remain symptom-free.

  Recruiting at 6 sites Phase 4 Copenhagen University Hospital, Rigshospitalet · Copenhagen, Region H and 5 other locations · NCT07268313

• Full-house endoscopic sinus surgery with or without nasopharyngeal lymphoid tissue ablation for nasal polyps

  This study will test whether adding nasopharyngeal lymphoid tissue ablation to full-house endoscopic sinus surgery helps adults with nasal polyps have less nasal inflammation and fewer recurrences.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT07245329

• Biologics in Chronic Rhinosinusitis With Nasal Polyps

  This study tests three biologic medicines to see which helps adults with chronic sinusitis and nasal polyps repayably improve symptoms and quality of life.

  Recruiting at 5 sites Phase 4 Medical University of South Carolina · Phoenix, Arizona and 4 other locations · NCT06824649

• Biologics for Chronic Rhinosinusitis with Nasal Polyps in France

  This registry follows adults with CRSwNP who are being treated with biologics (dupilumab, mepolizumab, or benralizumab) to see how these therapies work in real-world clinical practice.

  Recruiting University Hospital, Lille · Lille and 1 other locations · NCT06501807

• Blocking Interleukin-4Ra with Dupilumab to Reduce Staphylococcus in Nasal Polyps

  This study is testing if a medication called dupilumab can help people with nasal polyps reduce harmful bacteria and improve their overall nasal health.

  Recruiting Phase 4 University of Virginia · Charlottesville, Virginia · NCT05094570

• Investigating Inflammatory Patterns in Asthma and Nasal Polyps

  This study is trying to see how asthma and nasal polyps are connected by looking at patients with both conditions to better understand their inflammation patterns.

  Recruiting Medical University of Vienna · Vienna · NCT05009758

• In-clinic removal of nasal polyps for chronic sinusitis

  This study tests if a new in-clinic procedure for removing nasal polyps can help people with chronic sinusitis just as much as the traditional surgery done in an operating room, while being quicker and cheaper.

  Recruiting at 4 sites Ottawa Hospital Research Institute · Vancouver, British Columbia and 3 other locations · NCT02975310

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Understanding how inner nose tissues go wrong in chronic nasal polyps

  Aimed at people with chronic rhinosinusitis with nasal polyps, this study looks at how tissue and cell signals drive inflammation and tissue changes in the nose.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11352000

Related topics

Quick answers

How many Nasal Polyps clinical trials are recruiting right now?

12, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (4 trials), Japan (2 trials), Puerto Rico (1 trial), Turkey (Türkiye) (1 trial), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 4, Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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