Drug or treatment

Tezepelumab clinical trials

• 11Clinical trials
• 40Countries

Newest trials

All recruiting trials (11)

• Structured physical activity program added to tezepelumab for adults with severe asthma

  A 12-week program to help adults with severe asthma who start tezepelumab see if adding guided physical activity improves activity levels and chances of remission.

  Recruiting University of Leeds · Leeds · NCT07735494

• Tezepelumab in real-world CRSwNP: a real-world look at patient outcomes

  This study tests tezepelumab in adults with chronic rhinosinusitis with nasal polyps to see how their symptoms and daily life change in routine care over about two years.

  Recruiting at 19 sites AstraZeneca · Berlin and 18 other locations · NCT07633158

• Tezepelumab for Chinese adults with nasal polyps: a 24-week treatment study

  This trial tests whether tezepelumab can improve nasal polyps and symptoms in Chinese adults with chronic rhinosinusitis with nasal polyps who are starting therapy.

  Recruiting at 34 sites Phase 3 AstraZeneca · Beijing and 33 other locations · NCT07520162

• Real-world use of tezepelumab for chronic rhinosinusitis with nasal polyps in Russia

  This study will see how tezepelumab works in adults in Russia who have chronic rhinosinusitis with nasal polyps, with or without asthma.

  Recruiting at 10 sites AstraZeneca · Kazan' and 9 other locations · NCT07399665

• Tezepelumab to reduce maintenance medication in people with severe asthma

  This will test whether people aged 12–80 with severe asthma in China who start tezepelumab can safely reduce their regular maintenance medicines while keeping asthma controlled.

  Recruiting at 59 sites Phase 3 AstraZeneca · Beijing and 74 other locations · NCT07363642

• Tezepelumab with Peanut OIT for Peanut Allergy

  This study tests whether adding tezepelumab to peanut oral immunotherapy can help people with peanut allergy build lasting tolerance.

  Recruiting at 6 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Little Rock, Arkansas and 9 other locations · NCT07015996

• Heart-event monitoring for people with severe asthma taking Tezepelumab (Tezspire)

  This project will test whether taking tezepelumab (Tezspire) changes the risk of serious heart problems in adolescents and adults with severe asthma compared with high-intensity standard care.

  Recruiting at 4 sites AstraZeneca · Wilmington, Delaware and 3 other locations · NCT06951867

• Evaluating Tezepelumab for Adults with Moderate to Very Severe COPD

  This study is testing if a new medication called tezepelumab can help adults with moderate to very severe COPD feel better and reduce flare-ups compared to a placebo.

  Recruiting at 259 sites Phase 3 AstraZeneca · Foley, Alabama and 304 other locations · NCT06883305

• Evaluating Tezepelumab for Adults with Moderate to Very Severe COPD

  This study is testing if a new medication called tezepelumab can help adults with moderate to very severe COPD feel better and reduce their flare-ups over a treatment period of up to 76 weeks.

  Recruiting at 233 sites Phase 3 AstraZeneca · Birmingham, Alabama and 283 other locations · NCT06878261

• Tezepelumab for adults with severe asthma presenting to the emergency department

  This study tests whether a monthly injection of tezepelumab, given in the emergency department, can reduce return visits for asthma flares in adults with severe asthma.

  Recruiting Phase 4 University of Alberta · Edmonton, Alberta and 1 other locations · NCT06705764

• Evaluating tezepelumab for severe asthma in children aged 5 to under 12

  This study is testing if a new asthma treatment called tezepelumab can help children aged 5 to under 12 who have severe asthma feel better and breathe easier.

  Recruiting at 117 sites Phase 3 AstraZeneca · Montgomery, Alabama and 146 other locations · NCT06023589

Quick answers

How many clinical trials of Tezepelumab are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 40 countries. The most sites are in United States (5 trials), China (4 trials), Canada (3 trials), France (3 trials), United Kingdom (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 5, Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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