Examining sleep issues in patients with nasal polyps

Effects of Endoscopic Sinus Surgery on Sleep Disorder in Patients With Chronic Rhinosinusitis With Polyps

Not applicable Interventional University Hospital, Lille · NCT03725956

This study looks at how nasal polyps affect sleep quality and whether surgery can help improve sleep for people who haven't found relief with other treatments.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital, Lille Academic / other
Locations1 site (Lille)
Trial IDNCT03725956 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of nasal polyposis on sleep quality and the effects of endoscopic sinus surgery on sleep disturbances. It focuses on patients who have undergone surgery for chronic rhinosinusitis with nasal polyps, particularly those who have not responded to corticosteroid treatment. The study aims to objectively assess sleep quality through polysomnography and analyze improvements post-surgery.

Who should consider this trial

Good fit: Ideal candidates are patients with chronic rhinosinusitis and nasal polyps who have not responded to corticosteroid therapy and are scheduled for endoscopic sinus surgery.

Not a fit: Patients who have had previous nasal surgery for polyposis or those already receiving continuous positive airway pressure therapy for obstructive sleep apnea may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies for patients suffering from sleep disturbances related to nasal polyposis.

How similar studies have performed: While few studies have objectively assessed the impact of nasal polyposis on sleep quality, this approach is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who underwent endoscopic sinus surgery for recalcitrant nasal polyposis (failure of a 4-month corticosteroid medical treatment) Social insured patient
* Patient willing to comply with all procedures of the study and its duration
* Patient giving consent

Exclusion Criteria:

* Patients with previous nasal surgery for nasal polyposis
* Patients with previous continuous positive airway pressure therapy for obstructive sleep apnea
* Non-coverage by the social security scheme
* Patient unable to receive informed information
* Refusal to sign the consent
* Person deprived of the liberty
* Person benefiting from a system of legal protection (guardianship…)

Where this trial is running

Lille

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Rhinosinusitis With Nasal PolypsObstructive Sleep ApneaNasal polyposissleepsinus surgerypolysomnographyquality of life
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.