Condition
Chronic Rhinosinusitis Without Nasal Polyps clinical trials and research
As of November 12, 2026, Find a Trial lists 4 Chronic Rhinosinusitis Without Nasal Polyps clinical trials that are recruiting, at sites in 3 countries (most in United States (2), Sweden (1), Austria (1)). By phase: Phase 2/3 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 3Countries
Newest Chronic Rhinosinusitis Without Nasal Polyps clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Sinonasal microbiome transplant for chronic rhinosinusitis | Phase 2/3 | Helsingborg | Recruiting | Sep 22, 2025 |
| OPN-375 (fluticasone) nasal spray twice daily for teens with chronic rhinosinusitis without nasal polyps | Phase 3 | Huntsville, Alabama and 23 other locations | Recruiting | Feb 27, 2025 |
| Investigating the effects of Dupilumab on nasal barrier function in chronic rhinosinusitis patients | — | Vienna, Austria | Recruiting | May 3, 2024 |
| Using 3D printing to enhance nasal irrigation for chronic rhinosinusitis | — | Columbus, Ohio | Recruiting | Nov 7, 2023 |
All recruiting trials (4)
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Sinonasal microbiome transplant for chronic rhinosinusitis
This will try a sinonasal microbiome transplant to see if it reduces symptoms in people with chronic rhinosinusitis with or without nasal polyps.
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OPN-375 (fluticasone) nasal spray twice daily for teens with chronic rhinosinusitis without nasal polyps
This study will test whether OPN-375 nasal spray (186 µg) given twice daily helps adolescents (12–17) with chronic rhinosinusitis without nasal polyps have fewer symptoms than placebo.
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Investigating the effects of Dupilumab on nasal barrier function in chronic rhinosinusitis patients
This study is testing if the medication Dupilumab can improve the nasal barrier function in people with chronic rhinosinusitis, especially those with nasal polyps.
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Using 3D printing to enhance nasal irrigation for chronic rhinosinusitis
This study is testing if 3D printed models of patients' noses can help people with chronic rhinosinusitis use nasal irrigation more effectively and feel better without surgery.
Related topics
Quick answers
How many Chronic Rhinosinusitis Without Nasal Polyps clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (2 trials), Sweden (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2/3: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.