Drug or treatment

Mepolizumab clinical trials

• 5Clinical trials
• 5Countries

Newest trials

All recruiting trials (5)

• Mepolizumab with or without in-office nasal polypectomy for chronic rhinosinusitis with nasal polyps

  This study tests whether adding mepolizumab, alone or with in-office nasal polypectomy, helps adults with chronic rhinosinusitis with nasal polyps who need biologic treatment.

  Recruiting at 7 sites Phase 4 Instituto de Investigación Marqués de Valdecilla · Barakaldo and 6 other locations · NCT07814924

• Stopping mepolizumab or dupilumab to see if nasal polyps stay in complete remission.

  This trial will test whether adults with well-controlled nasal polyps who have been on mepolizumab or dupilumab can safely stop the biologic and remain symptom-free.

  Recruiting at 6 sites Phase 4 Copenhagen University Hospital, Rigshospitalet · Copenhagen, Region H and 5 other locations · NCT07268313

• Investigating the Role of Nasal Microbiome in Eosinophilic Granulomatosis with Polyangiitis

  This study is trying to see how the bacteria in the nose affect the immune system in people with Eosinophilic Granulomatosis with Polyangiitis and related conditions, and whether a new treatment can change that.

  Recruiting University Medical Center Groningen · Groningen · NCT06298448

• Identifying biomarkers for response to mepolizumab in patients with nasal polyps and asthma

  This study is testing if mepolizumab can help people with nasal polyps and asthma feel better, while also looking for signs that show who will benefit from the treatment.

  Recruiting at 2 sites Aristotle University Of Thessaloniki · Thessaloniki, Exochi and 1 other locations · NCT05708300

• Understanding asthma flare-ups in patients treated with mepolizumab

  This study looks at how asthma flare-ups happen in people taking mepolizumab over two years to better understand their symptoms and inflammation.

  Recruiting Laval University · Québec, Quebec · NCT04578171

Quick answers

How many clinical trials of Mepolizumab are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in Spain (1 trial), Greece (1 trial), Netherlands (1 trial), Canada (1 trial), Denmark (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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