Condition

Advanced Renal Cell Carcinoma clinical trials and research

• 10Clinical trials
• 2NIH research projects
• 7Countries

Newest Advanced Renal Cell Carcinoma clinical trials

All recruiting trials (10)

• Sitagliptin Plus Pembrolizumab in Advanced Renal Cell Carcinoma and Melanoma

  This study tests whether adding sitagliptin to pembrolizumab is safe and might help people whose advanced kidney cancer or melanoma stopped responding to prior PD-1/PD-L1 therapy.

  Recruiting Phase 1 University of Iowa · Iowa City, Iowa · NCT07634380

• Morning versus afternoon immunotherapy for advanced or metastatic solid tumors

  This trial tests whether giving standard immune checkpoint inhibitor therapy in the morning versus the afternoon changes outcomes for adults with advanced or metastatic solid tumors.

  Recruiting Phase 4 OHSU Knight Cancer Institute · Portland, Oregon · NCT07405086

• SHR-8068 with Adebrelimab and other anti-tumor drugs for advanced renal cell carcinoma

  This trial will test whether adding SHR-8068 to Adebrelimab (with or without other anti-cancer drugs) helps people with advanced clear cell renal cell carcinoma.

  Recruiting Phase 1/2 Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Beijing, Beijing Municipality · NCT07239596

• PF-08634404 alone and with other anticancer medicines for adults with advanced kidney cancer.

  This tests whether PF-08634404, given alone or with other cancer medicines, is safe and helps adults with locally advanced or metastatic kidney cancer who have not had prior systemic treatment.

  Recruiting at 157 sites Phase 1/2 Pfizer · Phoenix, Arizona and 182 other locations · NCT07227415

• Combination of XL092 and Immunotherapy for Advanced Clear Cell Kidney Cancer

  This study is testing if a new drug called XL092, alone or with another treatment called nivolumab, can help people with advanced clear cell kidney cancer who haven't responded well to previous therapies.

  Recruiting at 5 sites Phase 2 Hoosier Cancer Research Network · La Jolla, California and 4 other locations · NCT06863311

• Comparing home and clinic administration of nivolumab for cancer treatment

  This study tests whether giving cancer patients their treatment at home instead of in a clinic makes them feel better and prefer their care more.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT06265285

• At-home cancer treatment versus clinic-based treatment for advanced cancer patients

  This study tests whether giving cancer treatment at home is better for comfort and satisfaction compared to getting it at a clinic for people with advanced cancer.

  Recruiting at 2 sites Phase 2 Mayo Clinic · Jacksonville, Florida and 1 other locations · NCT05969860

• Combining two treatments for patients with certain solid tumors

  This study is testing if combining a radioactive treatment with another drug can help people with certain solid tumors, like advanced kidney cancer, feel better and improve their condition.

  Recruiting at 5 sites Phase 1 Telix Pharmaceuticals (Innovations) Pty Limited · North Ryde, New South Wales and 4 other locations · NCT05868174

• Evaluating OATD-02 for advanced solid tumors

  This study is testing a new oral medication called OATD-02 to see if it can help people with advanced solid tumors, like colorectal and ovarian cancer, by making their tumors respond better to treatment.

  Recruiting at 3 sites Phase 1 Molecure S.A. · Bydgoszcz, Kuyavian-Pomeranian Voivodeship and 2 other locations · NCT05759923

• Combining Tumor Treating Fields with Cabozantinib or Pembrolizumab and Nab-Paclitaxel for Advanced Solid Tumors

  This study is testing a new treatment that combines tumor treating fields with two different cancer drugs to see if it helps people with advanced solid tumors in the abdomen or chest.

  Recruiting Phase 1 M.D. Anderson Cancer Center · Houston, Texas · NCT05092373

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Gut bacteria and immunotherapy outcomes in advanced kidney cancer

  This project compares people’s gut bacteria to their responses and side effects from immunotherapy for advanced kidney cancer.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11284115

• The role of gut bacteria in cancer treatment outcomes for kidney cancer patients

  This study is looking at how the bacteria in your gut might influence how well immunotherapy works for people with advanced kidney cancer, aiming to find out which gut bacteria can help predict treatment success and side effects, so doctors can better personalize care for each patient.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11060888

Related topics

Quick answers

How many Advanced Renal Cell Carcinoma clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (7 trials), Australia (2 trials), China (2 trials), Poland (1 trial), Germany (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 4, Phase 2: 3, Phase 1/2: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →