Condition

Advanced Lung Cancer clinical trials and research

• 17Clinical trials
• 9NIH research projects
• 12Countries

Newest Advanced Lung Cancer clinical trials

All recruiting trials (17)

• Nurse-led support for caregivers of older adults with advanced lung cancer

  This study tests a nurse-led care and resource system to support older adults with advanced lung cancer and their family caregivers.

  Recruiting at 2 sites National Taiwan University Hospital · Taipei, Taipei and 1 other locations · NCT07708870

• Managing chemotherapy side effects with a smartphone symptom app plus telenursing

  This trial tests whether a smartphone symptom-reporting app combined with a standardized telenursing program helps adults starting first-cycle chemotherapy for gastric, lung, breast, or colon cancer manage treatment side effects.

  Recruiting at 4 sites Ulsan University Hospital · Busan and 4 other locations · NCT07405931

• Tiered Palliative Care for Patients with Advanced Heart Failure or Cancer

  This trial tests a home-based, tiered palliative care program to see if more personalized support improves symptoms and quality of life for adults with advanced heart failure or certain advanced cancers.

  Recruiting at 5 sites Icahn School of Medicine at Mount Sinai · Astoria, New York and 4 other locations · NCT07391956

• TQB6411 injection for advanced lung cancer.

  This trial will test whether TQB6411 injection is safe and can help people with advanced lung cancer.

  Recruiting Phase 1/2 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Beijing, Beijing Municipality and 37 other locations · NCT07367529

• JS212 combo therapy for advanced lung cancer

  This trial tests JS212 with different partners to see if it can help adults with advanced non-small cell or extensive small cell lung cancer.

  Recruiting Phase 2 Shanghai Junshi Bioscience Co., Ltd. · Shanghai, Shanghai Municipality · NCT07309276

• MHB036C given with other cancer medicines for advanced lung cancer

  This study will try MHB036C together with other cancer medicines in adults with advanced lung cancer to see if the combination is safe and helps control tumors.

  Recruiting Phase 1/2 Minghui Pharmaceutical (Hangzhou) Ltd · Shanghai, Shanghai Municipality · NCT07229599

• PROMOTE mobile app to improve physical function and wellbeing in lung cancer survivors

  This project tests whether the PROMOTE mobile app can help adults with stage I–III non-small cell lung cancer undergoing curative chemotherapy improve their physical function and overall wellbeing.

  Recruiting Massachusetts General Hospital · Boston, Massachusetts · NCT07227623

• Targeted CAR-T Immunotherapy for Advanced Lung Cancer

  This study is testing a new CAR-T cell treatment for people with advanced lung cancer to see if it can effectively target and kill cancer cells that have a specific marker.

  Recruiting Phase 1 Chongqing Precision Biotech Co., Ltd · Nanjing, Jiangsu · NCT06992583

• CAR-T therapy targeting a specific tumor marker in advanced lung cancer

  This study is testing a new CAR-T therapy aimed at a specific tumor marker in patients with advanced lung cancer to see if it can help them after other treatments have failed.

  Recruiting Phase 1 Chongqing Precision Biotech Co., Ltd · Wuhan, Hubei · NCT06945523

• Inhaled mRNA vaccine for advanced lung cancer and lung metastasis

  This study is testing a new inhaled vaccine for people with advanced lung cancer to see if it can help them feel better and work well with other treatments.

  Recruiting Early Phase 1 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing · NCT06928922

• CAR-T therapy for advanced lung cancer targeting CEA

  This study is testing a new CAR-T therapy for people with advanced lung cancer that targets a specific marker to see if it can help those who haven't improved with regular treatments.

  Recruiting Phase 1 Chongqing Precision Biotech Co., Ltd · Shanghai · NCT06903117

• Investigating a new combination therapy for advanced lung cancer

  This study is testing a new combination treatment for advanced lung cancer to see if it’s safe and effective for patients.

  Recruiting at 91 sites Phase 1/2 BioNTech SE · Phoenix, Arizona and 90 other locations · NCT06892548

• A brief nurse-delivered program plus a digital app to help with breathlessness in advanced lung cancer

  This trial tests whether a short, nurse-led program plus a digital app can help reduce breathlessness in adults with advanced lung cancer.

  Recruiting Massachusetts General Hospital · Coral Gables, Florida and 1 other locations · NCT06791057

• Targeting CEA in Advanced Lung Cancer with CAR-T Therapy

  This study is testing a new CAR-T therapy for people with advanced lung cancer to see if it can help them after other treatments have failed.

  Recruiting Phase 1 Chongqing Precision Biotech Co., Ltd · Wuhan, Hubei · NCT06768151

• Evaluating BBO-10203 for advanced solid tumors

  This study is testing a new treatment called BBO-10203, alone and with another drug, to see if it can help people with advanced solid tumors, including certain types of breast cancer.

  Recruiting at 43 sites Phase 1 TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) · Duarte, California and 43 other locations · NCT06625775

• Psychosocial intervention for managing symptoms in advanced cancer patients

  This study is testing a new telehealth program called ENGAGE to see if it can help people with advanced cancer manage their symptoms and improve their quality of life.

  Recruiting Duke University · Durham, North Carolina · NCT06555588

• Palliative care for patients with advanced heart failure or cancer

  This study is testing a new palliative care program for people with advanced heart failure or cancer to see if it can improve their quality of life and reduce hospital visits compared to standard care.

  Recruiting Icahn School of Medicine at Mount Sinai · New York, New York · NCT06228209

NIH-funded research (9)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Spatial control of immunogenic cancer killing for locally advanced lung cancer

  A new approach uses radiation-triggered nanoparticles to deliver cancer-killing drugs directly to lung tumors while sparing healthy tissue.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11428611

• Predicting how function, thinking, and life quality change in older adults with advanced lung cancer

  This project aims to better predict how older adults with advanced non-small cell lung cancer will fare in daily living, thinking, and overall well‑being during treatment.

  NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11401395

• Pathways: a hopeful program to help advanced lung cancer patients pursue personal goals and improve well-being

  A brief, hope-based program helps adults with advanced lung cancer stay connected to goals in family, work, and daily life to support mental health and quality of life during treatment.

  NIH research University of Kentucky · Lexington, United States · NIH-11379102

• Comprehensive genetic testing for advanced lung cancer

  This project looks at how using wide genetic testing that checks hundreds of cancer genes might help people with advanced non-small cell lung cancer and influence care decisions and costs.

  NIH research Yale University · New Haven, United States · NIH-11179330

• Inhalable treatment for advanced lung cancer using engineered Influenza A virus

  This study is testing a new inhalable treatment for lung cancer that has spread, using a specially designed virus to help your body fight the cancer while keeping healthy cells safe, and it’s aimed at improving survival for patients like you.

  NIH research Accurius Therapeutics, INC. · Lexington, United States · NIH-11166802

• Brief behavioral support to help breathlessness in advanced lung cancer

  A multi-site study tests a short behavioral program delivered by nurses to help adults with advanced lung cancer feel less breathless and more able to do daily activities.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11130485

• Pathways: Supporting Mental Health and Quality of Life for People with Advanced Lung Cancer

  This project offers a new program called "Pathways" to help people with advanced lung cancer achieve their personal goals and improve their well-being during treatment.

  NIH research University of Kentucky · Lexington, United States · NIH-11129695

• Investigating the use of broad genomic profiling in advanced lung cancer treatment

  This study is looking at how using broad genomic profiling can help doctors make better treatment choices for patients with advanced non-small cell lung cancer, so they can get the most effective care based on their individual genetic makeup.

  NIH research Yale University · New Haven, United States · NIH-10932365

• A hope-based program to help lung cancer patients pursue personal goals and improve their mental health.

  This study is testing a new program called 'Pathways' to help people with advanced lung cancer focus on their personal goals and improve their mental well-being while they receive treatment.

  NIH research University of Kentucky · Lexington, United States · NIH-10893571

Related topics

Quick answers

How many Advanced Lung Cancer clinical trials are recruiting right now?

17, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in China (9 trials), United States (7 trials), Taiwan (2 trials), Australia (2 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 5, Phase 1/2: 3, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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