Predicting how function, thinking, and life quality change in older adults with advanced lung cancer

Who could benefit from this research

What this research studies

Older adults with non-small cell lung cancer often experience more treatment-related toxicity, which can affect their ability to function, think clearly, and enjoy life. The project seeks to develop patient-centered predictions of how these survivorship outcomes unfold over time, helping patients and doctors choose treatments that balance effectiveness with quality of life. Researchers will use data from diverse older patients to identify factors that influence trajectories of function, cognition, and quality of life during therapy, including immunotherapy with or without chemotherapy. The goal is to provide personalized information to support shared decision-making for treatment options in advanced cancer. This work could lead to better guidance on who might tolerate specific therapies and when supportive care or alternative strategies are appropriate.

Why it matters

Where this research is happening

• Kaiser Foundation Research Institute
  Oakland, United States Active

Researchers

• Principal investigator: Wong, Melisa L — Kaiser Foundation Research Institute
• Study coordinator: Wong, Melisa L

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.