PROMOTE mobile app to improve physical function and wellbeing in lung cancer survivors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will randomize adults with stage I–III non-small cell lung cancer who are within six weeks of starting curative-intent chemotherapy (with or without immunotherapy) to use the PROMOTE digital health app or receive enhanced usual care consisting of health education materials. The PROMOTE app delivers behavioral support for physical activity, breathlessness and sleep management, and healthy eating, and collects patient-reported outcomes over the treatment period. The primary outcome is patient-reported physical function, with secondary outcomes including dyspnea, sleep disturbance, physical activity, eating behaviors, self-efficacy, mood symptoms, and quality of life. Investigators will also explore mediators and moderators to understand who benefits most from the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Diagnosis of stage I-III non-small cell lung cancer
* Within six weeks of initiating treatment with curative intent that includes chemotherapy ± immunotherapy in the neo-adjuvant or adjuvant setting with surgery or as part of definitive chemoradiation
* Eastern Cooperative Oncology Group Performance Status = 0-2 (i.e., fully active to at least ambulatory and up and about more than 50% of waking hours)
* Ability to use a digital health intervention that includes verbal and written information in English
* Ability to complete questionnaires in English or Spanish
* Primary cancer care at one of the participating institutions

Exclusion Criteria:

* Significant uncontrolled psychiatric disorder or other co-morbid disease (e.g., dementia, cognitive impairment), which the treating oncology clinician reports would prohibit the patient's ability to participate in study procedures

Where it's running

• Massachusetts General Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Joseph A. Greer, PhD
• Email: jgreer2@mgh.harvard.edu
• Phone: 617-643-2143

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.