Condition

Advanced Esophageal Squamous Cell Carcinoma clinical trials and research

• 8Clinical trials
• 8Countries

Newest Advanced Esophageal Squamous Cell Carcinoma clinical trials

All recruiting trials (8)

• SHR-9839 alone or with chemotherapy plus adebrelimab in advanced esophageal squamous cell cancer

  This trial tests SHR-9839 by itself or with chemotherapy and adebrelimab to see if it helps people with advanced ESCC.

  Recruiting at 2 sites Phase 2 Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Beijing, Beijing Municipality and 1 other locations · NCT07751341

• Tislelizumab with chemotherapy in first-line advanced ESCC in Japanese patients

  This study tests whether giving tislelizumab every 2 weeks or every 4 weeks with standard chemotherapy can safely and effectively treat Japanese patients with newly diagnosed, unresectable or metastatic esophageal squamous cell carcinoma.

  Recruiting at 4 sites Phase 2 BeOne Medicines · Yokohama, Kanagawa and 3 other locations · NCT07733180

• YL201 vs physician's choice chemotherapy in advanced esophageal squamous cell carcinoma

  This study tests whether a new drug called YL201 works better or is safer than standard chemotherapy in adults with advanced or metastatic esophageal squamous cell cancer whose first treatment stopped helping.

  Recruiting at 80 sites Phase 3 MediLink Therapeutics (Suzhou) Co., Ltd. · Anqing, Anhui and 80 other locations · NCT07487896

• JS212 plus JS001 and 5‑FU for advanced esophageal squamous cell carcinoma

  This will test whether combining JS212 with JS001 and 5‑FU helps people with advanced esophageal squamous cell carcinoma who have not had prior systemic anti‑cancer therapy.

  Recruiting Phase 2 Shanghai Junshi Bioscience Co., Ltd. · Beijing, Beijing Municipality · NCT07484724

• AK112 combined with chemotherapy for advanced esophageal cancer

  This study is testing if a new drug called AK112, when combined with chemotherapy, can help people with advanced esophageal cancer who haven't had treatment before.

  Recruiting Phase 2 Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT06489197

• Comparing home and clinic administration of nivolumab for cancer treatment

  This study tests whether giving cancer patients their treatment at home instead of in a clinic makes them feel better and prefer their care more.

  Recruiting Phase 2 Mayo Clinic · Jacksonville, Florida · NCT06265285

• Testing a new antibody treatment for advanced squamous cell cancers

  This study is testing a new antibody treatment combined with chemotherapy for people with advanced squamous cell cancers that haven't responded to standard therapies.

  Recruiting at 17 sites Phase 1/2 Hummingbird Bioscience · Sydney, New South Wales and 19 other locations · NCT05910827

• Combination of Penpulimab and Chemotherapy for Advanced Esophageal Cancer

  This study is testing if adding Anlotinib to Penpulimab and chemotherapy can help people with advanced esophageal cancer feel better compared to just using Penpulimab and chemotherapy alone.

  Recruiting Phase 2 Nanfang Hospital, Southern Medical University · Guangzhou, Guangdong · NCT05214222

Related topics

Quick answers

How many Advanced Esophageal Squamous Cell Carcinoma clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in China (5 trials), Japan (1 trial), Australia (1 trial), Moldova (1 trial), Singapore (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →