Condition

Adjuvant Therapy clinical trials and research

• 13Clinical trials
• 11NIH research projects
• 3Countries

Newest Adjuvant Therapy clinical trials

All recruiting trials (13)

• Adjuvant sintilimab after neoadjuvant therapy and surgery for high-risk NSCLC

  This trial tests whether giving sintilimab after surgery helps prevent cancer from returning in people with high-risk non-small cell lung cancer who already had neoadjuvant immunochemotherapy and surgery.

  Recruiting at 2 sites Phase 2 Sichuan University · Chengdu, Sichuan and 1 other locations · NCT07748325

• Maintenance with QL1706 after chemo in high-risk triple-negative breast cancer

  This study tests whether adding QL1706 after standard chemotherapy can help people with high-risk triple-negative breast cancer stay cancer-free longer.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT07622836

• Antibody-armored dendritic cell therapy for people with solid tumors

  This will test a single injection of antibody-armored dendritic cells in adults with certain resected solid tumors after standard adjuvant chemotherapy to see if it is safe and stimulates an immune response.

  Recruiting Phase 1 Shanghai Cell Therapy Group Co.,Ltd · Shanghai · NCT07479667

• Breast cancer relapse after adjuvant CDK4/6 inhibitor therapy

  This project will look at people with HR+/HER2- early breast cancer who received adjuvant ribociclib or abemaciclib plus endocrine therapy to see what their tumor features and outcomes are, including those who relapse during or within 12 months after treatment.

  Recruiting at 11 sites European Institute of Oncology · Bergamo, Italy and 17 other locations · NCT07180693

• Adding a CDK4/6 blocker to hormone treatment after surgery for high-risk HR+/HER2+ early breast cancer

  This trial tests whether adding a CDK4/6 inhibitor to standard hormone therapy after surgery helps women aged 18–70 with high-risk HR+/HER2+ early breast cancer.

  Recruiting Phase 3 Fudan University · Shanghai · NCT07019363

• Evaluating the effects of adjuvant therapy after surgery for liver cancer

  This study is testing if additional treatment after surgery can help people with a rare and aggressive type of liver cancer do better.

  Recruiting West China Hospital · Chengdu, Sichuan · NCT06950814

• Reducing sitting time and increasing daily activity during cancer treatment

  This project will try a digital self-management program plus physiotherapist support to help people with breast, prostate, or colorectal cancer who are starting neo- or adjuvant treatment sit less and feel better during and after treatment.

  Recruiting at 2 sites Mälardalen University · Uppsala and 1 other locations · NCT06719206

• Using donafenib after surgery for liver cancer

  This study is testing if the drug donafenib can help prevent liver cancer from coming back in patients who have just had surgery to remove their tumors.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT06581315

• Combining irinotecan liposome with oxaliplatin and tegafur for pancreatic cancer treatment

  This study tests if a new combination of chemotherapy drugs can help people who have had surgery for pancreatic cancer recover better and stay cancer-free longer.

  Recruiting The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT06361316

• Neoantigen vaccine combined with anti-PD1 and chemotherapy for pancreatic cancer treatment

  This study is testing a new vaccine combined with anti-PD1 therapy and chemotherapy to see if it helps prevent pancreatic cancer from coming back after surgery.

  Recruiting Phase 1 Sichuan University · Chengdu, Sichuan · NCT06344156

• Combining Tislelizumab with Chemotherapy for Esophageal Cancer Treatment

  This study is testing if combining a new immune therapy called tislelizumab with chemotherapy can help people with esophageal cancer live longer and stay cancer-free after surgery.

  Recruiting Phase 2 Shanghai Chest Hospital · Shanghai, Shanghai Municipality · NCT06056336

• Befotertinib for treating early-stage non-small cell lung cancer with specific mutations

  This study is testing if a new drug called Befotertinib can help people with early-stage non-small cell lung cancer and specific mutations feel better after surgery compared to an existing treatment.

  Recruiting at 3 sites Phase 3 Betta Pharmaceuticals Co., Ltd. · Beijing and 2 other locations · NCT06041776

• Comparing targeted therapies for HER2 positive early breast cancer after surgery

  This study is testing whether a new combination of treatments can help women with HER2 positive early breast cancer do better after surgery compared to sticking with their original therapy.

  Recruiting Phase 2 Fujian Medical University Union Hospital · Fuzhou, Fujian · NCT05292742

NIH-funded research (11)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• XoLacta adjuvant therapy to reduce radiation side effects during HER2-positive breast cancer treatment

  A new milk-derived therapy called XoLacta aims to lessen radiation-related side effects for people undergoing treatment for HER2-positive breast cancer.

  NIH research Tiny Cargo Company, the · Roanoke, United States · NIH-11413717

• Navigation-based care pathway to speed adjuvant therapy for head and neck cancer

  A practical program tests a navigation-driven approach to help patients with head and neck cancer start postoperative radiation on time, aiming to improve survival.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11387560

• AI that combines scans, pathology slides, and records to guide post-surgery treatment for colorectal cancer

  This project uses artificial intelligence to combine CT/MRI scans, pathology slides, and medical records to help doctors decide which people with stage I–III colorectal cancer should get additional treatment after surgery.

  NIH research Stanford University · Stanford, United States · NIH-11319803

• XoLacta to reduce radiation side effects in HER2-positive breast cancer

  XoLacta, a milk-derived therapy given during radiation, aims to help people with HER2-positive breast cancer heal better and have fewer side effects.

  NIH research Tiny Cargo Company, the · Roanoke, United States · NIH-11254142

• Urothelial resurfacing with targeted electric pulses for bladder cancer

  A new treatment approach uses a pulse-based ablation to remove cancerous tissue in the bladder and help intravesical therapies work better for bladder cancer patients.

  NIH research University of Massachusetts Amherst · Hadley, United States · NIH-11225861

• Helping people with head and neck cancer start post-surgery radiation on time

  This project uses a patient navigation program to help people with head and neck cancer begin their recommended post-surgery radiation within six weeks of surgery.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11143127

• Milk-derived extracellular vesicles as a systemic radiotherapeutic and cancer adjuvant therapy

  A new milk-derived therapy loaded with a drug aims to help people exposed to high-dose radiation by healing the GI tract and bone marrow and could also support cancer treatment.

  NIH research Tiny Cargo Company, the · Roanoke, United States · NIH-11102389

• Using machine learning to improve treatment decisions for colorectal cancer patients after surgery

  This study is looking to improve treatment decisions for patients with colorectal cancer who have had surgery by using smart computer technology to analyze their medical information and images, helping doctors find out who might need extra therapy to prevent the cancer from coming back.

  NIH research Stanford University · Stanford, United States · NIH-11066505

• Improving timely cancer treatment for head and neck cancer patients

  This study is testing a helpful program that guides patients with head and neck cancer to make sure they get their radiation therapy on time, especially for those who might not have easy access to care.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-10867408

• Predicting cancer recurrence and treatment benefits for early-stage lung cancer patients

  This study is working on a new test that looks at 7 specific genes to help predict if early-stage lung cancer might come back after surgery and to see if extra chemotherapy could be helpful for patients who have had surgery for stage 1 non-small cell lung cancer.

  NIH research Sostos LLC · Morgantown, United States · NIH-10821728

• Improving blood flow during exercise for boys with Duchenne muscular dystrophy

  This study is looking at whether a medication called tadalafil can help boys with Duchenne muscular dystrophy (DMD) improve their blood flow during exercise, which might make it easier for them to be active and recover afterward.

  NIH research University of Florida · Gainesville, United States · NIH-10735090

Related topics

Quick answers

How many Adjuvant Therapy clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in China (11 trials), Sweden (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Phase 3: 2, Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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