Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating the effects of adjuvant therapy after surgery for liver cancer

Official title: Prognostic Impact of Adjuvant Therapy Following Surgical Resection in Primary Hepatic Sarcomatoid Carcinoma: A Retrospective Cohort Study

Run by West China Hospital · NCT06950814 · Data updated 2026-11-12

This study is testing if additional treatment after surgery can help people with a rare and aggressive type of liver cancer do better.

More Liver Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment50 (estimated)
SponsorWest China Hospital
Academic / other
Drugs / interventionsradiation
Locations1 site (Chengdu, Sichuan)
StatusRecruiting
StartedApril 5, 2025
Main results expectedMay 3, 2025
Study endsMay 5, 2025
Registry record updatedApril 30, 2025
Trial IDNCT06950814 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have undergone liver resection and have been diagnosed with primary hepatic sarcomatoid carcinoma.

Probably not a fit

Patients who received other anti-tumor treatments prior to surgery or have concurrent malignancies may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the potential benefits of postoperative adjuvant therapy in patients diagnosed with primary hepatic sarcomatoid carcinoma, a rare and aggressive form of liver cancer. By conducting a retrospective analysis at a single center, the study aims to gather clinical evidence regarding the effectiveness of adjuvant therapy following surgical resection. The research focuses on patients who have undergone liver resection and have had their pathology and immunohistochemistry results reviewed to confirm their diagnosis. The findings could help establish guidelines for treatment in this under-researched area.

Why it matters

Potential benefit: If successful, this study could provide insights that lead to improved treatment strategies for patients with primary hepatic sarcomatoid carcinoma.

How similar studies have gone: While there is limited clinical evidence specifically for primary hepatic sarcomatoid carcinoma, other studies on adjuvant therapy in liver cancer have shown varying degrees of success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. patients who underwent liver resection
2. patients' postoperative paraffin pathology and immunohistochemistry results were reviewed to identify those diagnosed with PHSC

Exclusion Criteria:

1. patients who received other anti-tumor treatments before surgery, such as radiofrequency ablation (RFA), transarterial chemoembolization (TACE), radiation therapy (RT), and systemic therapy;
2. patients diagnosed with other specific types of sarcomas;
3. patients with concurrent other malignancies during the course of PHSC;
4. patients who were lost to follow-up or lacked essential clinical data.

Where it's running

  • West China Hospital
    Chengdu, Sichuan, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.