Condition

CDK4/6 Inhibitor clinical trials and research

• 5Clinical trials
• 2Countries

Newest CDK4/6 Inhibitor clinical trials

All recruiting trials (5)

• Combination therapy with IN10018 and dalpiciclib for progressive meningioma

  This phase 1 study tests whether taking IN10018 with dalpiciclib is safe and tolerable in adults with growing meningiomas to see if the combo can help control the tumor.

  Recruiting Phase 1 Capital Medical University · Beijing, Beijing Municipality and 1 other locations · NCT07652762

• Dalpiciclib plus hormone therapy for early HR+/HER2- breast cancer

  This trial tests whether adding dalpiciclib at two different doses and durations to standard hormone therapy helps people with early HR+/HER2- breast cancer.

  Recruiting Phase 2 Fujian Cancer Hospital · Fuzhou, Fujian and 1 other locations · NCT07581834

• Breast cancer relapse after adjuvant CDK4/6 inhibitor therapy

  This project will look at people with HR+/HER2- early breast cancer who received adjuvant ribociclib or abemaciclib plus endocrine therapy to see what their tumor features and outcomes are, including those who relapse during or within 12 months after treatment.

  Recruiting at 11 sites European Institute of Oncology · Bergamo, Italy and 17 other locations · NCT07180693

• Predicting outcomes for advanced breast cancer patients treated with CDK4/6 inhibitors and endocrine therapy

  This study is trying to see how well different CDK4/6 inhibitors combined with hormone therapy work for people with advanced breast cancer and how safe they are.

  Recruiting at 24 sites Fondazione IRCCS Istituto Nazionale dei Tumori, Milano · Aviano and 23 other locations · NCT06805812

• Assessing safety of combining radiotherapy with new systemic therapies for breast cancer

  This study is testing if it's safe to give new breast cancer treatments together with radiation therapy to see if they can work well together for patients who need both.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality · NCT06197581

Related topics

Quick answers

How many CDK4/6 Inhibitor clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in China (3 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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