Using fecal microbiota to treat gut acute graft-versus-host disease
Department of Hematology of First Affiliated Hospital of Soochow University
This study is testing whether fecal microbiota transplantation can help improve gut symptoms in patients with acute graft-versus-host disease after stem cell transplantation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 10 Years to 60 Years |
| Sex | All |
| Sponsor | The First Affiliated Hospital of Soochow University Academic / other |
| Locations | 1 site (Suzhou, Jiangsu) |
| Trial ID | NCT03148743 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the safety and efficacy of fecal microbiota transplantation (FMT) in patients suffering from gut acute graft-versus-host disease (aGVHD) following stem cell transplantation. Patients diagnosed with gut GVHD will be recruited to assess how FMT can potentially improve their condition. The study aims to gather data on the outcomes of FMT in this specific patient population, contributing to the understanding of treatment options for gut GVHD.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with gut acute graft-versus-host disease.
Not a fit: Patients over the age of 60 or under the age of 10 will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a new therapeutic option for patients suffering from gut aGVHD.
How similar studies have performed: While this approach is being explored, the specific application of FMT for gut aGVHD is still relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * gut GVHD Exclusion Criteria: * Age\>60; or Age\<10
Where this trial is running
Suzhou, Jiangsu
- 中国 — Suzhou, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: xiaofei qi
- Email: qixiaofei@suda.edu.cn
- Phone: 1-86-512-67780410
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.