Clinical trial Recruiting at 1 site Observational Ages 18 to 100

What predicts death in the ICU? Analyzing APACHE II in Colombian patients

Official title: Factors Associated With Mortality in the Intensive Care Unit From the Orinoco Region. An Observational Trial

Run by Hospital Departamental de Villavicencio · NCT07249749 · Data updated 2026-11-12

This study tests how well the APACHE II score predicts ICU mortality in adults treated at a Colombian hospital.

Quick facts

Study typeObservational
Ages18 Years to 100 Years
SexAll
Enrollment1000 (estimated)
SponsorHospital Departamental de Villavicencio
Academic / other
Locations1 site (Villavicencio, Meta Department)
StatusRecruiting
StartedJanuary 10, 2026
Main results expectedDecember 20, 2028
Study endsDecember 21, 2028
Registry record updatedMay 27, 2026
Trial IDNCT07249749 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adult patients (18 years or older) admitted to the ICU at Hospital Departamental de Villavicencio during January 2022 to June 2025.

Probably not a fit

Patients with intermediate-care needs or those transferred to other facilities are unlikely to benefit from this predictive assessment.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, retrospective cohort study at Hospital Departamental de Villavicencio. Researchers collected data on adult ICU patients admitted between January 2022 and June 2025, calculating APACHE II scores at admission and tracking outcomes to compare mortality by disease type and admission source. They aim to determine which factors are associated with death in the ICU and to validate how accurately APACHE II predicts mortality in this population. The study uses consecutive cases from the ICU discharge database, excluding intermediate-care admissions and transfers to other facilities. Findings could inform local prognostic use of APACHE II and help tailor critical care planning in this setting.

Why it matters

Potential benefit: If APACHE II is found to predict mortality accurately, clinicians could better identify high-risk patients and allocate resources accordingly.

How similar studies have gone: Prior studies have used APACHE II in various settings, with mixed validation; this study aims to confirm performance in a Colombian ICU context.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All adult patients older than 18 admitted to the intensive care unit during the study period.

Exclusion Criteria:

* Patients admitted for intermediate care (low therapeutic intervention with a TISS \[Therapeutic Intervention Scoring System\] - 28 score below 20 points). Patients derived to other institutions.

Where it's running

  • Hospital Departamental de Villavicencio
    Villavicencio, Meta Department, Colombia
    Recruiting

Study contacts

  • Principal investigator: Norton Perez Gutierrez, MD — Hospital Departamental de Villavicencio
  • Study coordinator: Norton Perez Gutierrez, MD
  • Email: norton.perez@hotmail.com
  • Phone: 3112517471

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.