What predicts death in the ICU? Analyzing APACHE II in Colombian patients
Official title: Factors Associated With Mortality in the Intensive Care Unit From the Orinoco Region. An Observational Trial
Run by Hospital Departamental de Villavicencio · NCT07249749 · Data updated 2026-11-12
This study tests how well the APACHE II score predicts ICU mortality in adults treated at a Colombian hospital.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Hospital Departamental de Villavicencio Academic / other |
| Locations | 1 site (Villavicencio, Meta Department) |
| Status | Recruiting |
| Started | January 10, 2026 |
| Main results expected | December 20, 2028 |
| Study ends | December 21, 2028 |
| Registry record updated | May 27, 2026 |
| Trial ID | NCT07249749 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult patients (18 years or older) admitted to the ICU at Hospital Departamental de Villavicencio during January 2022 to June 2025.
✕Probably not a fit
Patients with intermediate-care needs or those transferred to other facilities are unlikely to benefit from this predictive assessment.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, retrospective cohort study at Hospital Departamental de Villavicencio. Researchers collected data on adult ICU patients admitted between January 2022 and June 2025, calculating APACHE II scores at admission and tracking outcomes to compare mortality by disease type and admission source. They aim to determine which factors are associated with death in the ICU and to validate how accurately APACHE II predicts mortality in this population. The study uses consecutive cases from the ICU discharge database, excluding intermediate-care admissions and transfers to other facilities. Findings could inform local prognostic use of APACHE II and help tailor critical care planning in this setting.
Why it matters
Potential benefit: If APACHE II is found to predict mortality accurately, clinicians could better identify high-risk patients and allocate resources accordingly.
How similar studies have gone: Prior studies have used APACHE II in various settings, with mixed validation; this study aims to confirm performance in a Colombian ICU context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All adult patients older than 18 admitted to the intensive care unit during the study period. Exclusion Criteria: * Patients admitted for intermediate care (low therapeutic intervention with a TISS \[Therapeutic Intervention Scoring System\] - 28 score below 20 points). Patients derived to other institutions.
Where it's running
-
Hospital Departamental de Villavicencio
Villavicencio, Meta Department, Colombia Recruiting
Study contacts
- Principal investigator: Norton Perez Gutierrez, MD — Hospital Departamental de Villavicencio
- Study coordinator: Norton Perez Gutierrez, MD
- Email: norton.perez@hotmail.com
- Phone: 3112517471
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.