Muscle Mass and Blood Gases in ICU Patients
Official title: An Investigation of The Relationship Between Muscle Mass, Physiological Parameters, and Blood Gas Levels in Adult Patients Hospitalized in The Intensive Care Unit
Run by Ankara Yildirim Beyazıt University · NCT07866625 · Data updated 2026-11-12
This study tests whether muscle mass in adults in the ICU is related to oxygen levels and other blood gas and vital signs.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Hours and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Ankara Yildirim Beyazıt University Academic / other |
| Locations | 1 site (Erzurum) |
| Status | Recruiting |
| Started | December 10, 2025 |
| Main results expected | December 10, 2026 |
| Study ends | December 10, 2026 |
| Registry record updated | October 8, 2026 |
| Trial ID | NCT07866625 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older admitted to selected ICUs (palliative, pulmonary, or cardiovascular) with a stable condition allowing muscle-mass measurement and informed consent.
✕Probably not a fit
Patients with conditions that prevent muscle-mass measurement or those lacking informed consent may not benefit from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this observational study, researchers will measure muscle mass in adult ICU patients using anthropometric techniques and compare it with arterial blood gas values, SpO2, heart rate, blood pressure, and urine output. The goal is to see if lower muscle mass is associated with poorer oxygenation and related physiological parameters. Data will come from patients in palliative care, pulmonary ICU, or cardiovascular ICU with at least 48 hours in the unit. The study discusses how muscle loss in critical illness can affect metabolism, respiratory strength, and recovery, and explores potential relationships with blood gas and oxygenation metrics.
Why it matters
Potential benefit: If a relationship is found, it could help clinicians anticipate oxygenation needs and recovery potential based on muscle mass.
How similar studies have gone: There is prior evidence linking muscle mass to respiratory function and outcomes in critical illness, but this specific relationship with blood gas values in ICU patients is not fully established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion Criteria: Age: Adult patients aged 18 years and older Clinical unit: Patients admitted to palliative care, pulmonary intensive care, or cardiovascular intensive care units Length of stay: Patients expected to remain in the intensive care unit for at least 48 hours Physical eligibility: Patients with no conditions preventing the measurement of muscle mass Clinical stability: Patients without severe hemodynamic instability or active bleeding at the time of measurement Ethical compliance: Individuals who have volunteered to participate in the study and whose informed consent has been obtained from them or their legal representative Exclusion Criteria: * Exclusion Criteria: * Patients with a history of previously diagnosed neuromuscular disorders (myasthenia gravis, Guillain-Barré syndrome, chronic polyneuropathies) * Patients with severe renal or hepatic insufficiency that could directly affect muscle mass * Presence of severe edema: Patients with a pitting edema score of 3+ or 4+ on the pitting edema test, or individuals with documented widespread edema in nursing or medical records * Patients with an amputation, hematoma, or open wound on the extremity to be measured * Pregnant patients * Patients whose intensive care stay lasted less than 48 hours or for whom the measurement could not be completed due to discharge or death
Where it's running
-
Erzurum City Hospital,
Erzurum, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Bihter AKINOĞLU — Ankara Yildiirm Beyazit University
- Study coordinator: Bihter Akınoğlu
- Email: RGKARDELEN@yahoo.com
- Phone: +905059384136
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.