Using renin levels to predict septic shock severity and outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the role of plasma renin concentration as a prognostic indicator for the severity of septic shock and patient outcomes. It focuses on patients aged 18 and older who are hospitalized in the intensive care unit with a confirmed diagnosis of sepsis within the last 24 hours. By analyzing renin levels alongside established markers like procalcitonin and lactate, the study seeks to fill gaps in the current understanding of sepsis severity assessment. The findings could lead to improved clinical decision-making in managing septic shock.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Hospitalization in the intensive care unit
* Confirmed diagnosis of Sepsis within 24 hours
* Signed informed consent or a decision by the medical council to include the patient in the study

Exclusion Criteria:

* Any surgical intervention on the kidneys and/or adrenal glands performed within 28 days prior to the patient's inclusion in the study
* Patients previously included in this study

Where it's running

• Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology
  Moscow, Russia Recruiting

Study contacts

• Principal investigator: Valery Likhvantsev, PhD — Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology
• Study coordinator: Valery Likhvantsev, PhD
• Email: lik0704@gmail.com
• Phone: +79036235982

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.