Using hyperbaric oxygen therapy after lower limb amputation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of additional hyperbaric oxygen therapy on healing after lower extremity amputation. Patients will be randomly assigned to either receive hyperbaric oxygen therapy or be placed in a control group. The goal is to enhance tissue oxygen levels in the amputation stump, potentially leading to better healing outcomes and reducing the need for further amputations. The study focuses on patients with chronic wounds, osteomyelitis, and ischemia who have undergone amputation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Lower extremity amputation because of chronic wound, osteomyelitis, ischemia, necrosis.
* Fit to receive hyperbaric oxygen therapy determined by an anesthesiologist/Hyperbaric Medicine Physician.
* Able to cooperate and follow up appointments
* Included within 7 days after final surgery

Exclusion Criteria:

* Not fulfilling inclusion criteria
* Pregnancy
* Dementia

Where it's running

• Diakonhjemmet Hospital
  Oslo, Norway Recruiting
• Orthopedic Center, Ullevål University Hopspital
  Oslo, Norway Recruiting

Study contacts

• Principal investigator: Jonas V Rydinge, MD — Ullevål University Hospital, orthopedic department
• Study coordinator: Jonas Rydinge, MD
• Email: jonryd@ous-hf.no
• Phone: +4792291795

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating human placental membrane products for treating nonhealing diabetic foot and venous leg ulcers

  This study is testing whether using human placental products along with regular care can help people with stubborn diabetic foot and leg ulcers heal better.

  Recruiting C5 Biomedical · Metairie, Louisiana · NCT06674980

• Comparing powered and mechanical prosthetic knees for K2-level amputees

  This study is testing whether powered prosthetic knees work better than mechanical ones for K2-level amputees to help improve their mobility and make better choices for future prosthetic designs.

  Recruiting Liberating Technologies, Inc. · Austin, Texas · NCT06194838

• Early angioplasty for diabetic foot syndrome

  This study is testing if getting a quick angioplasty after being diagnosed with diabetic foot ulcers helps heal the wounds better than waiting for the procedure.

  Recruiting Heinrich-Heine University, Duesseldorf · Düsseldorf · NCT06124586

• Integrated oral care for dry mouth in adults with diabetes

  This study will test whether simple oral care steps given by diabetes doctors during routine clinic visits can reduce dry mouth and improve oral health for adults with diabetes.

  Recruiting Khyber Medical University Peshawar · Peshawar, KPK · NCT07425275

• Effect of EMG sensor number and placement on control of below-elbow prosthetic arms

  This project will test whether changing the number and placement of myoelectric sensors helps adults with below-elbow limb absence control a prosthetic arm better while wearing a real device.

  Recruiting Liberating Technologies, Inc. · Chicago, Illinois and 1 other locations · NCT07011420

• Microprocessor-controlled prosthetic knees for limited community ambulators with above-knee amputation.

  This test will see if switching to a microprocessor-controlled prosthetic knee reduces fall-related health problems and improves walking speed, mobility, and quality of life for adults with above-knee amputations who are limited community ambulators compared with non-microprocessor knees.

  Recruiting Hanger Institute for Clinical Research and Education, LLC · Austin, Texas · NCT06937242

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.