Using FTIRS to detect and limit spread of ESBL-producing bacteria in ICUs

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Multidrug-resistant Enterobacterales, particularly ESBL-producing strains, pose a high risk of cross-transmission in intensive care units. This interventional study implements routine FTIRS typing of ESBL-E from rectal swabs to deliver rapid (about one hour) strain identification that can inform infection-control measures. FTIRS results will be used alongside standard culture workflows, recognizing whole genome sequencing (WGS/MLST/SNP) as the gold standard but less feasible for continuous surveillance. The study will compare cross-transmission rates before and after systematic FTIRS implementation to determine its impact on ESBL-E spread in the ICU.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients hospitalized in ICU
* ESBL-E carrier

Exclusion Criteria:

* none

Where it's running

• Chu Chen
  Caen, France Recruiting

Study contacts

• Principal investigator: Camille Jeanne-Leroyer, PharmD — Caen Normandie Hospital
• Study coordinator: Camille Jeanne-Leroyer
• Email: jeanneleroyer-c@chu-caen.fr
• Phone: +33(0)231065947

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.