Beacons for ICU: extra clinician alerts in ICU sub-units
Official title: ICU Background Early Awareness for Critical deterioratiON (BEACON)
Run by ETH Zurich · NCT07119411 · Data updated 2026-11-12
This study tests whether adding the ICU Beacon clinician awareness system to standard ICU care improves outcomes for adults with respiratory or circulatory failure compared with standard care alone.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1962 (estimated) |
| Sponsor | ETH Zurich Academic / other |
| Locations | 1 site (Bern) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | May 1, 2027 |
| Study ends | November 1, 2027 |
| Registry record updated | June 15, 2026 |
| Trial ID | NCT07119411 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults admitted to the ICU who meet criteria and consent or have appropriate consent documented, without age under 18 or other exclusion criteria.
✕Probably not a fit
Patients who do not experience worsening events or who are not managed with Beacon scores during their stay may see no additional benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, cluster-randomized crossover study in two ICU units (Blue and Yellow) at Inselspital, Bern. Sub-units within each ICU are randomized to receive ICU Beacon or standard care, with a wash-out period before swapping assignments. Patients admitted to sub-units receive outcomes assessed by blinded assessors, using a win-ratio composite and stratified by APACHE score at admission. Analysis follows a two-phase design, with censoring of patients crossing between sub-units and those transferred between units. The study investigates whether adding the ICU Beacon scoring system can reduce deterioration and improve organ function outcomes in critically ill adults.
Why it matters
Potential benefit: If successful, the ICU Beacon system could help clinicians detect deterioration earlier and potentially reduce organ dysfunction and mortality in ICU patients.
How similar studies have gone: Previous studies of clinician alert systems in ICUs have shown mixed results; this trial uses a rigorous, cluster-randomized crossover design to clarify potential benefits.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * admission to intensive care unit Exclusion Criteria: * age \< 18 years * presence of documented refused general consent form (at database closure) * admission for the sole purpose of dying/organ donation or evaluation of such
Where it's running
-
Inselspital - Universitätsspital Bern
Bern, Switzerland Recruiting
Study contacts
- Study coordinator: Gunnar Rätsch, Dr. rer. nat.
- Email: raetsch@ethz.ch
- Phone: +41 44 632 2036
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.