Electronic archive for treating severe organ failure and liver transplantation
Official title: Electronic Archive of Internal Medicine for the Treatment of Severe Organ Failure and Liver Transplantation-MITIGO
Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06781502 · Data updated 2026-11-12
This study looks at medical records of patients with severe liver failure to see how well different treatments work and improve liver transplant care over the next 10 years.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna Academic / other |
| Locations | 1 site (Bologna, Bologna) |
| Status | Recruiting |
| Started | October 21, 2023 |
| Main results expected | October 2033 |
| Study ends | October 2033 |
| Registry record updated | January 17, 2025 |
| Trial ID | NCT06781502 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older diagnosed with acute or chronic liver disease or those who have undergone liver transplantation.
✕Probably not a fit
Patients without a diagnosis of liver disease or organ failure will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study collects structured data from medical records of patients with acute or chronic liver failure. It includes both retrospective data from patients diagnosed since 2013 and prospective data from patients diagnosed after the study begins, continuing for a period of 10 years. The aim is to analyze treatment outcomes and improve understanding of liver transplantation and organ failure management.
Why it matters
Potential benefit: If successful, this study could enhance treatment strategies for patients with severe liver conditions and improve transplantation outcomes.
How similar studies have gone: Other observational studies have shown success in improving treatment outcomes for liver transplantation and organ failure, suggesting this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of acute or chronic liver disease or LT * Age ≥ 18 years * Obtaining informed consent Exclusion Criteria: * no one
Where it's running
-
IRCCS - Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy Recruiting
Study contacts
- Principal investigator: Giovanni Vitale, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Study coordinator: Giovanni Vitale, MD
- Email: giovanni.vitale@aosp.bo.it
- Phone: 0512144187
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Everolimus-based calcineurin-free immunosuppression one year after liver transplant
This trial tests whether switching to or using everolimus with reduced calcineurin inhibitors after year one post-liver transplant can protect kidney function while maintaining graft health in adults at low rejection risk.
-
Sleep quality and its determinants during the liver transplant pathway
This study tests how sleep quality changes from before liver transplantation to six months after, in adults on the transplant waitlist at a single hospital.
-
Preoperative CIMT and Intraoperative Hemodynamics in Liver Transplant
This study looks at whether a higher carotid IMT measured before surgery is linked to more unstable blood pressure during liver transplant.
-
Reference framework for outcomes after machine-preserved liver transplantation in Europe
This study tests how liver transplants that use machine perfusion perform in real-world practice, to see how different perfusion methods relate to outcomes for adults in Europe.
-
Even protein distribution plus exercise for people awaiting liver transplant
This trial tests whether spreading daily protein evenly and combining it with a 12-week exercise program improves nutrition, muscle mass, and function in people waiting for a liver transplant compared with uneven protein timing or usual advice.
-
Preoperative Carbohydrate Loading Before Liver Transplant
This study tests whether drinking a carbohydrate beverage before anesthesia helps liver transplant patients recover faster.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.