Using electronic notifications to improve management of severe aortic stenosis

Electronic Physician Notification to Facilitate the Recognition and Management of Severe Aortic Stenosis: The DETECT AS Trial

NA · Massachusetts General Hospital · NCT05230225

This study is testing if sending electronic reminders to doctors can help improve the care and treatment decisions for patients with severe aortic stenosis.

Quick facts

PhaseNA
Study typeInterventional
Enrollment940 (estimated)
Ages18 Years and up
SexAll
SponsorMassachusetts General Hospital (other)
Locations1 site (Boston, Massachusetts)
Trial IDNCT05230225 on ClinicalTrials.gov

What this trial studies

The DETECT AS Trial is a randomized clinical initiative aimed at enhancing the recognition and management of severe aortic stenosis (AS) through electronic physician notifications. Patients diagnosed with severe AS, defined by an aortic valve area of less than 1.0 cm², will have their ordering providers randomly assigned to receive either an electronic notification or no intervention. This notification will include relevant clinical practice guidelines to assist providers in making informed decisions regarding aortic valve replacement (AVR) and addressing disparities in AVR utilization among different ethnic and racial groups.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with severe aortic stenosis as indicated by echocardiography.

Not a fit: Patients who have bioprosthetic or mechanical valves in the aortic position will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved management and treatment outcomes for patients with severe aortic stenosis.

How similar studies have performed: Other studies have shown success with electronic notifications in improving clinical outcomes, suggesting this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects with severe aortic stenosis having an aortic valve area of less than or equal to 1.0cm2.

Exclusion Criteria:

* Subjects with bioprosthetic or mechanical valves in the aortic position

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Aortic Stenosis, Aortic Valve Stenosis, Aortic Valve Disease, Heart Valve Diseases, Heart Diseases, Cardiovascular Diseases, Aortic Valve Replacement

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.