Using antibiotics before bladder Botox injections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates whether not using antibiotic prophylaxis before bladder Botox injections is as safe as using antibiotics. Participants will be randomly assigned to receive either antibiotics or no treatment prior to their Botox procedure. The study aims to reduce unnecessary antibiotic use, addressing the issue of antibiotic resistance, while monitoring for urinary tract infections and other related complications. Follow-up assessments will occur two weeks and six weeks post-treatment to evaluate outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* Age ≥ 18
* Patient undergoing bladder Botox treatment

Exclusion Criteria:

* Pregnant and/or breastfeeding
* Contraindication to injection of Botox - hypersensitivity to any botulinum toxin preparation or to any of the components in the formulation, symptomatic urinary retention or post void residual (PVR) \> 200 mL, unwillingness or inability to initiate clean intermittent catheterization (CIC) post-treatment if required.
* Contraindication to oral antibiotics - hypersensitivity or allergy
* Inability to take medication by mouth

Where it's running

• Atlantic Health
  Morristown, New Jersey, United States Recruiting

Study contacts

• Principal investigator: Carolyn Botros, DO — Atlantic Health System
• Study coordinator: Anastasiya Holubyeva, MD
• Email: anastasiya.holubyeva@atlantichealth.org
• Phone: 9739717267

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.