Use of enamel matrix derivative with immediate implants in the lower back teeth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial compares immediate dental implants placed after extracting a non-restorable mandibular molar, with or without enamel matrix derivative (Emdogain). Outcomes include implant stability and peri-implant bone changes measured over six months using resonance frequency analysis and CBCT imaging. The study is conducted at Mansoura University’s Oral and Maxillofacial Surgery Department and involves 24 patients divided equally between the two groups. The goal is to determine if enamel matrix derivative improves healing and bone preservation around immediate implants in the mandibular molar region.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with non-restorable mandibular molar requiring dental extraction.
2. Patient medically free from systemic diseases that absolutely contraindicate implant surgery.
3. Age range: from (18 to 45) years.
4. Adequate inter-arch relation and inter-occlusal space to accommodate the prosthetic restoration (8-12mm).
5. Extraction sockets with intact bony walls and interradicular bone.
6. Jumping gap more than 2mm.
7. Patients with good oral hygiene.
8. Patients willing to participate in the study's follow-up intervals.

Exclusion Criteria:

1. Patients with any pathological lesion or aggressive periodontal disease at the planned surgical site impaired the immediate implant placement.
2. smoker patients.
3. Pregnant patients.
4. Patients with para-functional habits (bruxism and clenching)

Where it's running

• Faculty of Dentistry, Mansoura University - Oral and Maxillofacial Surgery Department
  Al Mansurah, Dakahlia Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Mohamad M Marwa, MSc
• Email: mohamad.marwa.1998@gmail.com
• Phone: +201140990087

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.