How full-arch dental implants affect oral health quality of life
Official title: Changes in Oral Health-related Quality of Life ( OHRQoL) Full Arch Implant Treatment: A Prospective Study
Run by Implantology Institute · NCT07568249 · Data updated 2026-11-12
This study will test whether full-arch implant-supported prostheses improve oral health-related quality of life and satisfaction for people who are missing most or all teeth.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Implantology Institute Academic / other |
| Locations | 1 site (Lisbon, Lisbon District) |
| Status | Recruiting |
| Started | November 1, 2025 |
| Main results expected | October 1, 2027 |
| Study ends | October 1, 2028 |
| Registry record updated | October 27, 2026 |
| Trial ID | NCT07568249 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
People who are systemically healthy, have an indication for full-arch implant rehabilitation in the maxilla or mandible, and can undergo implant surgery are ideal candidates.
✕Probably not a fit
Patients with medical contraindications to implant therapy, insufficient local anatomy for implants without major grafting, or who do not require full-arch rehabilitation are unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective observational cohort following patients receiving immediate full-arch implant-supported rehabilitation with 4, 6, or 8 implants per arch and screw-retained acrylic provisional prostheses followed by definitive prostheses after 3–6 months. Patient-reported outcomes will be measured at five time points using OHIP-14 and PIDAQ to track changes from baseline through one month after definitive prosthesis delivery. The study will compare outcomes by arch (maxilla versus mandible), by provisional versus definitive stages, and by definitive prosthetic material (monolithic zirconia, veneered zirconia, or hybrid prosthesis). Data will describe trajectories of oral-health quality of life and patient satisfaction over the course of treatment.
Why it matters
Potential benefit: If successful, the findings could help clinicians choose prosthesis types and timing that lead to better daily function and satisfaction for patients missing teeth.
How similar studies have gone: Prior work shows high long-term implant survival and improved short-term patient satisfaction with full-arch implants, but long-term effects on oral-health quality of life and differences by prosthetic material are less well documented.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adults aged 18 years or older. Patients requiring full-arch implant-supported rehabilitation of the maxilla and/or mandible. Patients with indication for immediate full-arch implant-supported rehabilitation using 4, 6, or 8 implants per arch, according to anatomical and clinical conditions. Patients able to understand the study procedures and complete patient-reported outcome questionnaires Patients willing to provide written informed consent. Exclusion Criteria: Patients with medical contraindications for implant surgery. Patients unable to provide informed consent. Patients unable to complete the study questionnaires Patients with uncontrolled systemic conditions that may contraindicate implant therapy. Patients unable or unwilling to attend the planned follow-up visits. Patients receiving partial-arch implant rehabilitation only.
Where it's running
-
Instituto de Implantologia
Lisbon, Lisbon District, Portugal Recruiting
Study contacts
- Principal investigator: Artur F Simões, Msc — Implantology Institute
- Study coordinator: Artur F Simões
- Email: filipesimoesmd@gmail.com
- Phone: +351962555077
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.