How full-arch dental implants affect oral health quality of life

Changes in Oral Health-related Quality of Life (OHRQoL) During Full Arch Implant Treatment: A Prospective Study

Observational Implantology Institute · NCT07568249

This study will test whether full-arch implant-supported prostheses improve oral health-related quality of life and satisfaction for people who are missing most or all teeth.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorImplantology Institute Academic / other
Locations2 sites (Lisbon, Lisbon District and 1 other locations)
Trial IDNCT07568249 on ClinicalTrials.gov

What this trial studies

This is a prospective observational cohort following patients receiving immediate full-arch implant-supported rehabilitation with 4, 6, or 8 implants per arch and screw-retained acrylic provisional prostheses followed by definitive prostheses after 3–6 months. Patient-reported outcomes will be measured at five time points using OHIP-14 and PIDAQ to track changes from baseline through one month after definitive prosthesis delivery. The study will compare outcomes by arch (maxilla versus mandible), by provisional versus definitive stages, and by definitive prosthetic material (monolithic zirconia, veneered zirconia, or hybrid prosthesis). Data will describe trajectories of oral-health quality of life and patient satisfaction over the course of treatment.

Who should consider this trial

Good fit: People who are systemically healthy, have an indication for full-arch implant rehabilitation in the maxilla or mandible, and can undergo implant surgery are ideal candidates.

Not a fit: Patients with medical contraindications to implant therapy, insufficient local anatomy for implants without major grafting, or who do not require full-arch rehabilitation are unlikely to benefit from this protocol.

Why it matters

Potential benefit: If successful, the findings could help clinicians choose prosthesis types and timing that lead to better daily function and satisfaction for patients missing teeth.

How similar studies have performed: Prior work shows high long-term implant survival and improved short-term patient satisfaction with full-arch implants, but long-term effects on oral-health quality of life and differences by prosthetic material are less well documented.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Systemically good health and absence of contraindications for implant therapy, with indication to be rehabilitated with at least one FASISR - maxilla or mandible.

Exclusion Criteria:

\-

Where this trial is running

Lisbon, Lisbon District and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Edentulous MouthQuality of LifeTooth LossOral Health Quality of Life Was Assesseddental implantoral healthoutcome studiesoral quality of life
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.