Understanding young onset colorectal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to create a comprehensive database to better understand young onset colorectal cancer, defined as cases diagnosed in individuals under 50 years old. Researchers will collect information through a risk factor questionnaire from participants diagnosed with gastrointestinal cancer and those diagnosed with colorectal adenocarcinoma over the age of 50. The goal is to analyze similarities and differences between young onset colorectal cancer and cases diagnosed later in life, facilitating current and future research in this area.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Participant Inclusion Criteria for database and questionnaire (YOGI)

* Histological or cytological diagnosis of gastrointestinal cancer
* 18 - 49 years old at time of consent
* No Known hereditary CRC or other cancer predisposition syndrome (stool collection cohort only)
* No history of inflammatory bowel disease (stool collection cohort only)
* No prior diagnosis of gastrointestinal cancer (stool collection cohort only)

Participant Inclusion Criteria for database and questionnaire (Controls)

* Histological or cytological diagnosis of colorectal adenocarcinoma
* No previous treatment for CRC (including surgery, chemotherapy, immunotherapy or radiation)
* Age 50 or older at time of consent
* No Known hereditary CRC or other cancer predisposition syndrome
* No history of inflammatory bowel disease
* No prior diagnosis of CRC

Where it's running

• Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
  Basking Ridge, New Jersey, United States Recruiting
• Memorial Sloan Kettering Monmouth
  Middletown, New Jersey, United States Recruiting
• Memorial Sloan Kettering Bergen
  Montvale, New Jersey, United States Recruiting
• Memorial Sloan Kettering Cancer Center @ Commack
  Commack, New York, United States Recruiting
• Memorial Sloan Kettering Westchester
  Harrison, New York, United States Recruiting
• MSK at Ralph Lauren
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Andrea Cercek, MD — Memorial Sloan Kettering Cancer Center
• Study coordinator: Andrea Cercek, MD
• Email: cerceka@mskcc.org
• Phone: 646-888-4189

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.