Impact of cancer treatments on reproductive and sexual health in young colorectal cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate how chemotherapy and radiation therapy affect reproductive and sexual health in individuals diagnosed with early onset colorectal cancer. Researchers will monitor changes in hormone levels and assess sexual and reproductive health through questionnaires. The goal is to gather valuable information that can enhance understanding of the implications of cancer treatments on fertility and overall quality of life for these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18-40 years of age and premenopausal (female) or 18-50 years of age (male) at time of diagnosis
* Histologic diagnosis of colorectal adenocarcinoma
* Able and willing to participate in the informed consent process
* Eligible for curative adjuvant or neoadjuvant therapy for colon or rectal cancer
* Willing and able to complete protocol questionnaires
* Rectal patients only: Individuals who will be receiving chemotherapy, followed by chemoradiotherapy (ChemoRT)

Exclusion Criteria:

* Prior systemic treatment for this malignancy
* Active or prior secondary malignancy
* History of ovarian resection (if female)
* Pregnant or nursing (lactating) women, where pregnancy is defined as the state of a female after conception until the termination of gestation, confirmed by a positive hCG laboratory test.

Where it's running

• Memorial Sloan Kettering Basking Ridge
  Basking Ridge, New Jersey, United States Recruiting
• Memorial Sloan Kettering Monmouth
  Middletown, New Jersey, United States Recruiting
• Memorial Sloan Kettering Bergen
  Montvale, New Jersey, United States Recruiting
• Memorial Sloan Kettering Cancer Center at Suffolk - Commack
  Commack, New York, United States Recruiting
• Memorial Sloan Kettering Westchester
  Harrison, New York, United States Recruiting
• Memorial Sloan Kettering Cancer Center
  New York, New York, United States Recruiting

Study contacts

• Principal investigator: Andrea Cercek, MD — Memorial Sloan Kettering Cancer Center
• Study coordinator: Andrea Cercek, MD
• Email: cerceka@mskcc.org
• Phone: 646-888-4189

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.