Clinical trial Recruiting at 1 site Interventional Ages 18 to 30

Understanding how different meals affect metabolism

Official title: Standardized Meals With Different Macronutrient Ratios on the Postprandial Metabolome and Metabolic Flexibility

Run by Instituto Nacional de Medicina Genomica · NCT06878781 · Data updated 2026-11-12

This study tests how different types of meals affect metabolism in young adults to see how their bodies respond to various nutrients.

Quick facts

Study typeInterventional
Ages18 Years to 30 Years
SexAll
Enrollment300 (estimated)
SponsorInstituto Nacional de Medicina Genomica
Government
Locations1 site (Mexico City)
StatusRecruiting
StartedJanuary 8, 2024
Main results expectedJanuary 30, 2026
Study endsDecember 18, 2026
Registry record updatedMarch 17, 2025
Trial IDNCT06878781 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy young adults aged 18 to 30 without any chronic health conditions.

Probably not a fit

Patients with existing metabolic disorders or those requiring medication for health conditions will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates metabolic flexibility, which is the body's ability to switch energy sources in response to different meals. Participants will consume standardized meals with varying macronutrient compositions, and their metabolic responses will be assessed through blood samples and dietary questionnaires. The study aims to provide insights into how these responses relate to metabolic health, particularly in young adults. Participants will be monitored weekly for one month to gather comprehensive data on their metabolic responses.

Why it matters

Potential benefit: If successful, this study could enhance understanding of metabolic health and inform dietary recommendations to prevent obesity and diabetes.

How similar studies have gone: While studies on metabolic flexibility exist, this specific approach using mixed meals with varied macronutrient ratios is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* be over 18 years of age and under 30 years of age;
* without active drug addictions: smoking, alcoholism, and/or drug addiction;
* in female subjects: regular menstrual cycles;
* give written consent for their inclusion in the study.

Exclusion Criteria:

* subjects with any pathology that requires medication or special treatment, such as type 2 diabetes mellitus, high blood pressure, dyslipidemia, polycystic ovary syn-drome, autoimmune, thyroid, kidney, neurological diseases, and cancer;
* pregnant or lactating women;
* subjects with problems with chewing, salivation, and swallowing.

Elimination criteria:

* subjects who only have samples (blood and calorimetry) from one study period (fasting or postprandial);
* subjects who only have samples (blood and calorimetry) of a metabolic challenge;
* subjects who have an infection at the scheduled appointment;
* subjects who withdraw their informed consent

Where it's running

  • Berenice Palacios-Gonzalez
    Mexico City, Mexico
    Recruiting

Study contacts

  • Principal investigator: Berenice Palacios-Gonzalez, PhD — National Institute of Genomic Medicine
  • Study coordinator: Berenice Palacios-Gonzalez, PhD
  • Email: bpalacios@inmegen.gob.mx
  • Phone: 5553501900

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.