Understanding how different meals affect metabolism
Official title: Standardized Meals With Different Macronutrient Ratios on the Postprandial Metabolome and Metabolic Flexibility
Run by Instituto Nacional de Medicina Genomica · NCT06878781 · Data updated 2026-11-12
This study tests how different types of meals affect metabolism in young adults to see how their bodies respond to various nutrients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Instituto Nacional de Medicina Genomica Government |
| Locations | 1 site (Mexico City) |
| Status | Recruiting |
| Started | January 8, 2024 |
| Main results expected | January 30, 2026 |
| Study ends | December 18, 2026 |
| Registry record updated | March 17, 2025 |
| Trial ID | NCT06878781 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy young adults aged 18 to 30 without any chronic health conditions.
✕Probably not a fit
Patients with existing metabolic disorders or those requiring medication for health conditions will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates metabolic flexibility, which is the body's ability to switch energy sources in response to different meals. Participants will consume standardized meals with varying macronutrient compositions, and their metabolic responses will be assessed through blood samples and dietary questionnaires. The study aims to provide insights into how these responses relate to metabolic health, particularly in young adults. Participants will be monitored weekly for one month to gather comprehensive data on their metabolic responses.
Why it matters
Potential benefit: If successful, this study could enhance understanding of metabolic health and inform dietary recommendations to prevent obesity and diabetes.
How similar studies have gone: While studies on metabolic flexibility exist, this specific approach using mixed meals with varied macronutrient ratios is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * be over 18 years of age and under 30 years of age; * without active drug addictions: smoking, alcoholism, and/or drug addiction; * in female subjects: regular menstrual cycles; * give written consent for their inclusion in the study. Exclusion Criteria: * subjects with any pathology that requires medication or special treatment, such as type 2 diabetes mellitus, high blood pressure, dyslipidemia, polycystic ovary syn-drome, autoimmune, thyroid, kidney, neurological diseases, and cancer; * pregnant or lactating women; * subjects with problems with chewing, salivation, and swallowing. Elimination criteria: * subjects who only have samples (blood and calorimetry) from one study period (fasting or postprandial); * subjects who only have samples (blood and calorimetry) of a metabolic challenge; * subjects who have an infection at the scheduled appointment; * subjects who withdraw their informed consent
Where it's running
-
Berenice Palacios-Gonzalez
Mexico City, Mexico Recruiting
Study contacts
- Principal investigator: Berenice Palacios-Gonzalez, PhD — National Institute of Genomic Medicine
- Study coordinator: Berenice Palacios-Gonzalez, PhD
- Email: bpalacios@inmegen.gob.mx
- Phone: 5553501900
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.