Improve Teen Sleep to Support Healthy Blood Sugar and Metabolism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls overweight high-schoolers aged 14-19 who sleep 7 hours or less on school nights. Each participant will experience two weeks of their usual sleep schedule followed by two weeks of a sleep-improvement plan that increases time in bed, adds melatonin, and uses morning light. The goal is to measure changes in blood sugar control and how the body uses energy during these periods. The study is conducted at Children’s Hospital Colorado with support from UC Denver and NIDDK.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. High school students between 14-19 years
2. Overweight/obesity (BMI \>85% for age and sex)
3. Have habitually insufficient sleep, defined as ≤ 7 hours per night on school days
4. Habitually inactive (≤ 3 h of physical activity reported per week)
5. Tanner stage 4 or 5, based on breast development for girls and testicular size for boys.

Exclusion Criteria:

1. Reported diagnosis of sleep disorder (e.g., insomnia, obstructive sleep apnea)
2. Medical comorbidities that impact sleep or insulin sensitivity (e.g., diabetes \[based on history or screening HbA1c\])
3. Regular use of medications affecting sleep or insulin sensitivity (e.g., stimulants, sleep aids, systemic steroids, insulin sensitizers, GLP-1 agonists)
4. IQ\<70 or severe mental illness that may impact sleep or study participation (e.g., schizophrenia), eating disorder, or active suicidal ideation
5. Schedules that would preclude participants from adhering to the sleep schedules (e.g., night-shift employment)

Where it's running

• Children's Hospital Colorado
  Aurora, Colorado, United States Recruiting

Study contacts

• Principal investigator: Stacey L Simon — University of Colorado, Denver
• Study coordinator: Stacey L Simon, PhD
• Email: stacey.simon@childrenscolorado.org
• Phone: 720-777-5681

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.