Triage performance and physiological predictors of serious illness in febrile children in the pediatric emergency department

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter prospective observational study enrolls children aged 0-18 with fever across 10 Turkish pediatric emergency departments to see how well the Ministry of Health’s color-coded triage (Red-Yellow-Green) predicts serious outcomes. It also evaluates whether physiological measurements taken at triage (heart rate, respiratory rate, oxygen saturation, capillary refill time, level of consciousness, and overall appearance) add prognostic value beyond triage alone. Triage decisions remain unchanged during care, and the study uses standardized forms and pre-specified statistical criteria to compare models with triage alone versus triage plus physiological data and laboratory variables. The primary outcome is a composite of serious events, with analyses including sensitivity, specificity, predictive values, likelihood ratios, and mixed-effects logistic regression to account for center differences.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 0-18 years
* Presentation to the pediatric emergency department
* Fever \>=38.0 C at triage OR history of fever within the preceding 24 hours

Exclusion Criteria:

* Presentation due to trauma
* Elective visits
* Missing triage data
* Re-attendance within 72 hours for the same episode (only the first visit is included)

Where it's running

• Erciyes University Faculty of Medicine
  Kayseri, Talas, Turkey (Türkiye) Recruiting
• Adana City Training and Research Hospital
  Adana, Turkey (Türkiye) Recruiting
• Cukurova University Faculty of Medicine
  Adana, Turkey (Türkiye) Recruiting
• Akdeniz University Faculty of Medicine
  Antalya, Turkey (Türkiye) Recruiting
• Osmangazi University Faculty of Medicine
  Eskişehir, Turkey (Türkiye) Recruiting
• Kartal Dr. Lutfi Kirdar City Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Yilmaz Secilmis — TC Erciyes University
• Study coordinator: Yilmaz Secilmis, MD
• Email: yilmazsecilmis@erciyes.edu.tr
• Phone: +905063013174

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.