Using antibiotics to prevent infections in patients with gastric varices undergoing treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to determine the necessity of antibiotic prophylaxis in patients with chronic liver disease and gastric varices who are treated with endoscopic variceal obturation (GVO). The study will involve a randomized approach to assess the effectiveness of Ertapenem in preventing septic infections and reducing the rebleeding rate associated with gastric variceal bleeding. Given the high rebleeding rates and potential complications from current treatment methods, this trial seeks to clarify the role of antibiotics in improving patient outcomes. Participants will be closely monitored for any adverse effects and treatment efficacy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with live cirrhosis and/or hepatoma
2. Aged 20 to 85, who had endoscopy-treatment EV(-)GV(+)or EV\<GV

Exclusion Criteria:

1. Had a terminal illness of any major organ system,such as heart failure, kindey failure,COPD
2. Patients recieve antibiotics recently.
3. Patients suspected infection.

Where it's running

• Veteran General Hospital-Taipei
  Taipei, Taiwan Recruiting

Study contacts

• Principal investigator: Ming-Chih Hou — Taipei Veterans General Hospital, Taiwan
• Study coordinator: Ming-Chih Hou, MD
• Email: mchou@vghtpe.gov.tw
• Phone: 886-2-28712111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.