Clinical trial Recruiting at 1 site Observational Ages 18 and up

Transducer levelling errors in everyday ICU practice

Official title: Transducer Levelling Errors in Everyday ICU Practice - A Multicentre Blinded Observational Study

Run by Vastra Gotaland Region · NCT07330505 · Data updated 2026-11-12

In critically ill, vasopressor-treated adults with arterial and central venous lines, this study tests how small height differences in pressure transducers may lead to measurement errors that could affect treatment decisions.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorVastra Gotaland Region
Government
Locations2 sites (Gothenburg and 1 other locations)
StatusRecruiting
StartedFebruary 1, 2026
Main results expectedMarch 1, 2027
Study endsMay 1, 2027
Registry record updatedJuly 7, 2026
Trial IDNCT07330505 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) in the ICU who are mechanically ventilated, have an arterial catheter for MAP and a central venous catheter for CVP, and are receiving vasopressor therapy.

Probably not a fit

Patients without invasive pressure monitoring or those not on vasopressors are unlikely to benefit from this observational work.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter observational study conducted in the ICU setting. It monitors arterial and central venous pressure readings to determine how transducer positioning errors translate into pressure deviations during routine care. A parallel reference setup provides blinded, continuous estimates of the true vertical level to quantify levelling deviations without altering clinical practice. Data are collected over an 8-hour period per participant, focusing on whether measured MAP and CVP deviations correlate with therapeutic actions such as vasopressor adjustments. The study does not mandate changes to standard care and aims to characterize the potential impact of levelling on decision-making.

Why it matters

Potential benefit: If successful, the findings could inform safer monitoring practices and reduce misinterpretation of invasive pressure readings in the ICU.

How similar studies have gone: Previous work suggests that transducer height can influence pressure readings, but multicenter, blinded data in routine ICU care are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years
* ICU admission
* Mechanically ventilated
* Arterial catheter for MAP
* Central venous catheter for CVP
* Ongoing vasopressor therapy

Exclusion Criteria:

* Severe hemodynamic or respiratory instability
* Contraindications for lateral positioning
* Expected survival \<24 hours

Where it's running

  • Sahlgrenska University Hospital
    Gothenburg, Sweden
    Recruiting
  • Skaraborgs Sjukhus
    Skövde, Sweden
    Not yet recruiting

Study contacts

  • Principal investigator: Lotta Johansson, PhD — Sahlgrenska University Hospital
  • Study coordinator: Carl Sjödin, PhD student
  • Email: carl.sjodin@vgregion.se
  • Phone: +46313421096

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.